Results 21 to 30 of about 5,174,691 (107)

Expression and regulation of transmembrane transporters in healthy intestine and gastrointestinal diseases [PDF]

open access: yes, 2006
Transmembrane transporters mediate energy dependent or independent translocation of drugs, potentially toxic compounds, and of various endogenous substrates such as bile acids and bilirubin across membranes.
Hruz, Petr
core   +1 more source

Anion channel sensitivity to cytosolic organic acids implicates a central role for oxaloacetate in integrating ion flux with metabolism in stomatal guard cells [PDF]

open access: yes, 2011
Stomatal guard cells play a key role in gas exchange for photosynthesis and in minimizing transpirational water loss from plants by opening and closing the stomatal pore.
Yizhou Wang   +5 more
core   +1 more source

SLC2A9 is a high-capacity urate transporter in humans [PDF]

open access: yes, 2008
Background Serum uric acid levels in humans are influenced by diet, cellular breakdown, and renal elimination, and correlate with blood pressure, metabolic syndrome, diabetes, gout, and cardiovascular disease. Recent genome-wide association scans have
Doblado M   +240 more
core   +1 more source

Neuronal and astroglial correlates underlying spatiotemporal Intrinsic Optical Signal in the rat hippocampal slice [PDF]

open access: yes, 2013
Widely used for mapping afferent activated brain areas in vivo, the label-free intrinsic optical signal (IOS) is mainly ascribed to blood volume changes subsequent to glial glutamate uptake.
Ildikó Pál   +11 more
core   +2 more sources

H+ és HCO3- transzporterek szabályozása humán pancreas ductus sejtekben = Regulation of H+ and HCO3-Transporters in Human Pancreatic Duct Cells [PDF]

open access: yes, 2009
A pancreas nedvben található HCO3- ionok kiválasztásáért a pancreas ductus sejtek felelősek. Jelen pályázatban célul tűztük ki, hogy molekuláris biológiai, transzdukciós és mikrofluorescens technikák felhasználásával megértsük a HCO3- szekréció ...
Rakonczay, Zoltán
core   +1 more source

Apical and basolateral localisation of GLUT2 transporters in human lung epithelial cells [PDF]

open access: yes, 2008
Glucose concentrations of normal human airway surface liquid are approximately 12.5 times lower than blood glucose concentrations indicating that glucose uptake by epithelial cells may play a role in maintaining lung glucose homeostasis.
Baines, DL   +15 more
core   +1 more source

Molecular pharmacology of renal organic anion transporters

open access: yes, 2000
Renal organic anion transport systems play an important role in the elimination of drugs, toxic compounds, and their metabolites, many of which are potentially harmful to the body.
Masereeuw, R.   +5 more
core   +1 more source

Fluorinated tetrapodal anion transporters [PDF]

open access: yes, 2023
Synthetic anion transporters show potential in treating life-threatening diseases like cystic fibrosis and cancer. However, with increasingly complex transporter architectures designed to control anion binding and transport, it is important to consider ...
Alexander M. Gilchrist   +9 more
core   +1 more source

Decreased expression of breast cancer resistance protein in the duodenum in patients with obstructive cholestasis [PDF]

open access: yes, 2006
Background/Aims: The expression of transporters involved in bile acid homeostasis is differentially regulated during obstructive cholestasis. Since the drug efflux transporter breast cancer resistance protein (BCRP) is known to transport bile acids, we ...
Beuers, Ulrich   +7 more
core   +1 more source

Transzcelluláris bikarbonát szekréció és intracelluláris pH reguláció polarizált epitheliás sejtekben = Transcellular bicarbonate secretion and intracellular pH regulation on polarized epithelial cells [PDF]

open access: yes, 2009
Kutatásunk célja polarizált epitheliális sejtek elektrolit és folyadékszekréciójának molekuláris szintű vizsgálata volt. Jól differenciált hasnyálmirigy duktusz Capan-1 és HPAF, valamint nyálmirigy acinus ParC10 és SMIE sejtvonalakat vizsgáltunk ...
Burghardt, Beáta
core   +1 more source

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