Results 181 to 190 of about 754,218 (305)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Quality assurance and harmonization for targeted biomonitoring measurements of environmental organic chemicals across the Children's Health Exposure Analysis Resource laboratory network. [PDF]

Int J Hyg Environ Health, 2021
Kannan K, Stathis A, Mazzella MJ, Andra SS, Barr DB, Hecht SS, Merrill LS, Galusha AL, Parsons PJ.   +8 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Integrating Monitoring and Biomonitoring Data with Mechanistic Models to Better Estimate and Characterize Aggregate Human Exposures to Semivolatile Organic Chemicals. [PDF]

Environ Sci Technol
Hughes L, Cops J, Geerts L, De Brouwere K, Sangion A, Li L, Arnot JA.   +6 more
europepmc   +1 more source

organic chemicals [PDF]

Chemical & Engineering News Archive, 1960
openaire   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Silicone Ankle Bands as a Tool to Assess Infant Exposures to Semivolatile Organic Chemicals in Indoor Environments. [PDF]

Environ Sci Technol Lett
Wise CF, Boxer E, Hurst J, Hoehn RM, Herkert NJ, Hay D, Cooper EM, Stapleton HM, Hoffman K.   +8 more
europepmc   +1 more source

Development and evaluation of two-parameter linear free energy models for the prediction of human skin permeability coefficient of neutral organic chemicals. [PDF]

J Cheminform, 2021
Naseem S, Zushi Y, Nabi D.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Comprehensive Characterization of Organic Chemicals Associated with Urban Particulate Matter in China. [PDF]

Environ Health (Wash)
Yao L, Guo Y, Wang Y, Li J, Sun J, Liu Y, Shi J, Qu G, Jiang G.   +8 more
europepmc   +1 more source