Results 1 to 10 of about 595,513 (253)
Organic chemistry as representation. [PDF]
Found Chem, 2021 Electron redistribution is the cornerstone of our understanding of chemical reactivity. For the vast majority of organic reactions electrons are assumed to move in pairs providing explanatory mechanisms through the generation of intermediate structures.
Healy EF.
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Physical organic chemistry [PDF]
Beilstein Journal of Organic Chemistry, 2010 Physical organic chemistry – the study of the interplay between structure and reactivity in organic molecules – underpins organic chemistry, and we cannot imagine organic chemistry as a subject without knowledge of mechanism and reactivity. It is sometimes thought that the golden age of ‘physical organic chemistry’ was in the 20th century, when ...
John A. Murphy
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iScience, 2021 Summary: Trifluoromethylated molecules have gained privileged recognition among the medicinal and pharmaceutical chemists. Sustainable photoredox- and electrochemical processes were employed to facilitate the relatively less explored radical cross ...
Muhammad Awais Ashraf +4 more
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Homologation of aryl ketones to long-chain ketones and aldehydes via C–C bond cleavage
iScience, 2022 Summary: Transition metal-catalyzed C–C bond cleavage is a powerful tool for the reconstruction of a molecular skeleton. We report herein the multi-carbon homologation of aryl ketones to long-chain ketones and aldehydes via ligand-promoted Ar−C(O) bond ...
Xing Wang +4 more
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Copper-mediated aerobic trifluoromethyltelluration of boronic acids with [Me4N][TeCF3]
iScience, 2022 Summary: A copper-mediated trifluoromethyltelluration of arylboronic acids with [Me4N][TeCF3] using air as an environmental friendly oxidant is presented. The reaction proceeded smoothly under mild conditions in the presence of Cu(OTf)2 and bipyridine to
Jing-Yan Dong +3 more
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iScience, 2022 Summary: A concise copper-catalyzed oxidative dehydrogenative dearomatization of indole derivatives for the direct synthesis of spirocyclic indolenines containing fluorene and indeno[2,1-b]indole groups has been established.
Junli Chao +6 more
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Fluorinated tetrapodal anion transporters
iScience, 2023 Summary: Synthetic anion transporters show potential in treating life-threatening diseases like cystic fibrosis and cancer. However, with increasingly complex transporter architectures designed to control anion binding and transport, it is important to ...
Alexander M. Gilchrist +4 more
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The serendipitous effect of KF in Ritter reaction: Photo-induced amino-alkylation of alkenes
iScience, 2021 Summary: Ritter reaction has been recognized as an elegant strategy to construct the C−N bond. Its key feature is forming the carbocation for nucleophilic attack by nitriles.
Yu-Qing Guan +6 more
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iScience, 2020 Summary: Over the past decades, asymmetric catalysis has been intensely investigated as a powerful tool for the preparation of numerous chiral biologically active compounds.
Huamin Wang +3 more
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iScience, 2023 Summary: Unanticipated formation of symmetrical sulfonyl guanidine was observed while treating isonitriles with N,N-dibromoarylsulfonamides in absence of an external amine source.
Debashish Mishra +2 more
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