Results 131 to 140 of about 602,948 (304)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Metabolic Stability of Fluorinated Small Molecules: A Physical Organic Chemistry Perspective. [PDF]

J Med Chem
Bhattarai P, Trombley TA, Altman RA.
europepmc   +1 more source

Impact of organic chemistry conditions on DNA durability in the context of DNA-encoded library technology. [PDF]

iScience, 2023
Sunkari YK, Nguyen TL, Siripuram VK, Flajolet M.   +3 more
europepmc   +1 more source

EASY EXPERIMENTS OF ORGANIC CHEMISTRY.

, 1899
Charles E. Munroe
openalex   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Markers of Excellence: Professional Development Opportunities in an Organic Chemistry CURE. [PDF]

J Chem Educ
Boyd EA, Andersen CI, Walker JP.
europepmc   +1 more source

Participation in a High-Structure General Chemistry Course Increases Student Sense of Belonging and Persistence to Organic Chemistry. [PDF]

J Chem Educ, 2023
Casey JR, Supriya K, Shaked S, Caram JR, Russell A, Courey AJ.   +5 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Advancing Organic Chemistry Using High-Throughput Experimentation. [PDF]

Angew Chem Int Ed Engl
Nsouli R, Galiyan G, Ackerman-Biegasiewicz LKG.   +2 more
europepmc   +1 more source

Making Enzymes Suitable for Organic Chemistry by Rational Protein Design. [PDF]

Chembiochem, 2022
Reetz M.
europepmc   +1 more source