Results 181 to 190 of about 1,588,412 (342)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Navigating between the worlds of mechanistic and synthetic organic chemistry. [PDF]

Tetrahedron
Jacobsen EN.
europepmc   +1 more source

Data Science Meets Physical Organic Chemistry. [PDF]

Acc Chem Res, 2021
Crawford JM, Kingston C, Toste FD, Sigman MS.   +3 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Bridging Organic Chemistry Teaching Laboratories and Real-World Research with Modern Computing and Spectroscopic Techniques. [PDF]

ACS Omega
Camp DM.
europepmc   +1 more source

Organic chemistry as representation. [PDF]

Found Chem, 2021
Healy EF.
europepmc   +1 more source

A Perspective on Free Radical Autoxidation: The Physical Organic Chemistry of Polyunsaturated Fatty Acid and Sterol Peroxidation

, 2013
Ned A. Porter
openalex   +2 more sources

Nitrogen oxide chemistry in an urban plume: investigation of the chemistry of peroxy and multifunctional organic nitrates with a Lagrangian model [PDF]

, 2009
I. M. Pérez, B. W. LaFranchi, R. C. Cohen   +2 more
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Tech-Enhanced Synthesis: Exploring the Synergy between Organic Chemistry and Technology. [PDF]

J Am Chem Soc
Bonciolini S, Pulcinella A, Noël T.
europepmc   +1 more source