Results 51 to 60 of about 1,298,228 (253)

Organic matter chemistry controls greenhouse gas emissions from permafrost peatlands [PDF]

open access: yes, 2016
Large tracts of arctic and subarctic peatlands are underlain by permafrost. These peatlands store large quantities of carbon (C), and are currently under severe threat from climate change.
A.P.S. Jurd   +76 more
core   +2 more sources

Morley's “Organic Chemistry” [PDF]

open access: yesNature, 1886
THE faults into which the writer of a text-book of organic chemistry for students is apt to be led are, as Dr. Morley points out in his preface, that of overelaboration on the one hand, to which the material too readily lends itself, and that of unintelligent abridgment on the other. Dr.
openaire   +3 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Preparation of o-Fluorobenzoic Acid. An Elementary Organic Laboratory Experiment [PDF]

open access: yes, 1971
An experiment designed for organic chemistry students at the sophomore level is presented. The experiment, which involves no special equipment and which employs only inexpensive reagents, demonstrates the conversion of anthranilic acid to o-fluorobenzoic
Setliff, Frank L.
core   +2 more sources

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

Organic chemistry on Titan [PDF]

open access: yes
Observations of nonequilibrium phenomena on the Saturn satellite Titan indicate the occurrence of organic chemical evolution. Greenhouse and thermal inversion models of Titan's atmosphere provide environmental constraints within which various pathways ...
Aronowitz, S.   +3 more
core   +1 more source

Machine Learning, Quantum Mechanics, and Chemical Compound Space

open access: yes, 2016
We review recent studies dealing with the generation of machine learning models of molecular and solid properties. The models are trained and validated using standard quantum chemistry results obtained for organic molecules and materials selected from ...
Adamo   +106 more
core   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

A Unified Monte Carlo Treatment of Gas-Grain Chemistry for Large Reaction Networks. II. A Multiphase Gas-Surface-Layered Bulk Model

open access: yes, 2012
The observed gas-phase molecular inventory of hot cores is believed to be significantly impacted by the products of chemistry in interstellar ices. In this study, we report the construction of a full macroscopic Monte Carlo model of both the gas-phase ...
Herbst, E., Vasyunin, A. I.
core   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

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