Results 41 to 50 of about 400,616 (308)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Design of Android Interactive Multimedia for the Concept of Aromatic Compound

open access: yesMATEC Web of Conferences, 2018
Some organic chemistry lectures material is abstract. The lack of development of appropriate learning media has become one of the causes of the difficulty of the student in understanding organic chemistry.
Amaliyah Laely   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Conjugated Polymers with Oligoethylene Glycol Side Chains for Improved Photocatalytic Hydrogen Evolution

open access: yesiScience, 2019
Summary: Conjugated polymers are emerging as promising organic photocatalysts for hydrogen evolution from water. However, it is still very challenging for conjugated polymers to realize highly efficient photocatalytic hydrogen evolution.
Zhicheng Hu   +6 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Physical Methods of Organic Chemistry [PDF]

open access: yesNature, 1946
VOLUME 1 on “Physical Methods of Organic Chemistry” which Interscience Publishers of New York have issued in a new series on “Techniques of Organic Chemistry” is one of the many recent American scientific books which will, on grounds of cost, probably be consulted in reference libraries by most English readers and not purchased for personal use. It has
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Solvent extraction (Organic Chemistry Lecture-Demonstrations)

open access: yes, 2022
This lecture-demonstration discusses extraction of a target analyte with an organic solvent using a separatory funnel, leading from understanding liquid-liquid extraction to obtaining a dry organic extract.
A/Prof Aimin Yu   +3 more
core  

Estimating European volatile organic compound emissions using satellite observations of formaldehyde from the Ozone Monitoring Instrument [PDF]

open access: yes, 2010
Emission of non-methane Volatile Organic Compounds (VOCs) to the atmosphere stems from biogenic and human activities, and their estimation is difficult because of the many and not fully understood processes involved.
P. I. Palmer   +10 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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