Results 111 to 120 of about 1,547,122 (263)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

In-situ synthesizing CoONAl-C catalysts from spent LiCoO2 batteries and tobacco stems biomass: nearly 100 ​% peroxymonosulfate utilization

Resources, Environment and Sustainability
Strategic metal recovery from spent lithium-ion batteries (LIBs) is urgently required novel technologies with high efficiency, low environmental impact, and strong economic viability.
Teng Guo, Xiaoya Gao, Xingxin Yang, Jiatian Wang, Yucheng Yin, Yaoran Hu, Yue Luo, Yongming Luo   +7 more
doaj   +1 more source

A Spitzer/IRS spectral study of a sample of galactic carbon-rich proto-planetary nebulae

, 2010
Recent infrared spectroscopic observations have shown that proto-planetary nebulae (PPNs) are sites of active synthesis of organic compounds in the late stages of stellar evolution.
Bernard-Salas, Bernard-Salas, Bruce J. Hrivnak, Cerrigone, Henry, Houck, Hrivnak, Hrivnak, Hu, Hudgins, Jones, Keller, Kelly, Kwok, Kwok, Kwok, Kwok, Meixner, Nakashima, Pendleton, Posch, Pottasch, Rosenthal, Scott, Sloan, Sloan, Smith, Speck, Sun Kwok, Suzuki, Van Kerckhoven, Volk, Volk, Volk, Werner, Yong Zhang, Zhang   +36 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Kinetic and Equilibrium Analysis of Tartrazine Photocatalytic Degradation Using Iron-Doped Biochar from Theobroma cacao L. Husk via Microwave-Assisted Pyrolysis

Chemistry Proceedings
The MAP process involved placing acid-pretreated biomass (CPH) in a domestic microwave oven at 600 W for 15 min. This was followed by a doping process with iron salts (+2, +3) to obtain BCCPH-Fe. Characterization of BCCPH-Fe was carried out using surface
Jean Espinoza, Elvia V. Cabrera, Ullrich Stahl, Jhonny Correa-Abril   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Designed Reactive Natural Deep Eutectic Solvents for Lipase-Catalyzed Esterification

Molecules
Natural deep eutectic solvents (NADESs) are a sustainable, green option for extraction and reaction media in biorefineries and various chemical and biotechnological applications.
Alina Ramona Buzatu, Anamaria Todea, Raluca Pop, Diana Maria Dreavă, Cristina Paul, Ioan Bîtcan, Marilena Motoc, Francisc Peter, Carmen Gabriela Boeriu   +8 more
doaj   +1 more source

Bioactive metabolites in crops, diets and human samples [PDF]

, 2007
The objective of the PhD-project is to characterize bioactive metabolites, such as polyphenols, in selected crops and investigate the influence of different organic farming systems on the ability of crops to synthesize bioactive compounds with health ...
Knuthsen, Pia, Nielsen, John, Søltoft, Malene   +2 more
core