Results 81 to 90 of about 1,547,122 (263)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Crystal structure of diaqua[bis(μ 2-pyridine 2,6-dicarboxylato) bismuth(III) potassium(I)], C14H10BiKN2O10

Zeitschrift für Kristallographie - New Crystal Structures
C14H10BiKN2O10, triclinic, P1̄ (no. 2), a = 7.029(8) Å, b = 10.460(9) Å, c = 11.891(9) Å, α = 71.19(2)°, β = 80.57(3)°, γ = 85.18(4)°, V = 815.9(13) Å3, Rgt (F) = 0.0512, wRref (F 2) = 0.1410, Z = 2, T = 296(2) K.
Wei-Hong Lu, Zu-Chen Hong, Jia-Hui Li, Miao Huang   +3 more
doaj   +1 more source

Novel six-coordinate Aryl- and Alkyltin complexes [PDF]

, 2002
Organo-tin compounds have wide applications as pesticides and as intermediates for organic synthesis.¹ They are invariably Sn(IV) derivatives and are generally four-coordinate.² The mixed organo/chioro compounds of the type RnSnCI4-n do however have the ...
Lloyd, Nicholas C., Nicholson, Brian K., Thomson, Ralph A., Wilkins, Alistair L.   +3 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Molecular Imprinted Polymers for Penicillins and Tetracyclines

Антибиотики и Химиотерапия, 2020
The molecular imprinted polymers (MIPs) for penicillins and tetracyclines described in the literature were analysed with a purpose of evaluating their possible use for the antibiotic sorption isolation.
M. I. Yakhkind, K. R. Tarantseva, M. A. Marynova, P. A. Storozhenko, M. M. Rasulov   +4 more
doaj  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The crystal structure of 3,7,11-trimethylbenzo[5,6][1,4]thiazino[2,3,4-kl]phenothiazine 5,5,9,9-tetraoxide, C21H17NO4S2

Zeitschrift für Kristallographie - New Crystal Structures
C21H17NO4S2, orthorhombic, Pna21 (no. 33), a = 15.028(3) Å, b = 14.045(3) Å, c = 8.9625(16) Å, V = 1891.7(6) Å3, Z = 4, Rgt(F) = 0.0359, wRref(F2) = 0.0870, T = 296 (2) K.
Tan Jing, Zhang Lingfeng, Ni Penghui
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Advances in ab-initio theory of Multiferroics. Materials and mechanisms: modelling and understanding

, 2012
Within the broad class of multiferroics (compounds showing a coexistence of magnetism and ferroelectricity), we focus on the subclass of "improper electronic ferroelectrics", i.e.
A. Girlando, A. Malashevic, A. Rohrbach, A. Savin, A. Seidl, A. Stroppa, A. Stroppa, A. Stroppa, A. Stroppa, A. Stroppa, A.D. Becke, A.K. Cheetham, A.K. Kirov, A.P. Kuzmenko, A.P. Levanyuk, A.V. Kimel, B. Lorenz, B.J. Campbell, C. Adamo, C. Capillas, C. Capillas, C. Capillas, C. Ederer, C. Ederer, C. Loschen, C.N.R. Rao, D. Baldomir, D. Khomskii, D. Orobengoa, D. Vanderbilt, D.I. Khomskii, D.V. Efremov, E. Bousquet, E. Bousquet, E. Kroumova, E. Kroumova, E. Kroumova, E. Kroumova, E.J.W. Verwey, E.M. Wheeler, F. Hong, F. Kagawa, F. Kagawa, F. Kubel, F. Nad, G. Férey, G. Férey, G. Giovannetti, G. Giovannetti, G. Giovannetti, G. Giovannetti, G. Giovannetti, G. King, G. King, G. King, G. King, G. King, G. Kresse, G. Kresse, G. Kresse, G. Lawes, G. Rogez, G.P. Vorobev, H. Katsura, H. Okamoto, H. Schmidt, H. Tsunetsugu, H. Wu, H.F. Clausen, I.A. Sergienko, I.A. Sergienko, I.B. Bersuker, I.J. Dzialoshinski, I.V. Solovyev, J. Adhish, J. Brink van den, J. Hemberger, J. Heyd, J. Heyd, J. Hong, J. Kanamori, J. Lopez-Prez, J. Paier, J. Valasek, J. Wang, J.A. Alonso, J.B. Goodenough, J.B. Torrance, J.B. Torrance, J.F. Scott, J.H. Lee, J.L. Garcia-Munoz, J.M. Perez-Mato, J.M. Perez-Mato, J.M. Perez-Mato, J.M. Rondinelli, J.M. Rondinelli, J.M. Rondinelli, J.M. Rondinelli, J.P. Perdew, K. Yamauchi, K. Yamauchi, K. Yamauchi, K. Yamauchi, K.-L. Hu, K.-L. Hu, K.I. Kugel, L. Holmes, L. Neel, L. Noodleman, L. Noodleman, L. Noodleman, L. Noodleman, L.C. Chapon, M. Alexe, M. Belakhovsky, M. Cointe Le, M. Dressel, M. Filatov, M. Marsman, M. Matsubara, M. Mostovoy, M. Reehuis, M.A. black, M.I. Aroyo, M.I. Aroyo, M.J. Rosseinsky, M.T. Fernandez-Diaz, M.W. Licurse, N. Keller, N.A. Benedek, N.A. Benedek, N.A. Hill, N.A. Spaldin, N.B. Perkins, N.J. Mosey, O. Tchernyshyov, O.M. Yaghi, P. Barone, P. García, P. Ghosez, P. Hohenberg, P. Jain, P.E. Blochl, P.J. Hay, P.J. Stephens, P.W. Anderson, P.W. Anderson, P.W. Anderson, R. Ramesh, R. Ramesh, R. Resta, R. Valdes-Aguilar, R. Wojciechowski, R.D. King-Smith, R.E. Cohen, R.L. Withers, S. Blanco-Canosa, S. Garcia-Martin, S. Garcia-Martin, S. Horiuchi, S. Horiuchi, S. Horiuchi, S. Horiuchi, S. Ishibashi, S. Ishiwata, S. Ivantchev, S. Ivantchev, S. Kummel, S. Picozzi, S. Picozzi, S. Picozzi, S. Valencia, S. Weber, S.C. Parida, S.J. Luo, S.L. Gnatchenko, S.W. Cheong, T. Fukushima, T. Fukushima, T. Fukushima, T. Hoffmann, T. Kimura, T. Kurumaji, T. Moriya, T. Smith, T. Zhao, T.-Y. Khim, V. Pardo, V.I. Anisimov, V.I. Anisimov, V.Y. Pomjakushin, W. Dachraoui, W. Kohn, X.-Y. Wang, Y. Du, Y. Miyamoto, Y. Nakatsuka, Y. Okimoto, Y. Takano, Y. Tokunaga, Y. Tokunaga, Y. Tokura, Y. Yamasaki, Z.G. Soos   +204 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source