Results 241 to 250 of about 80,743 (315)

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

open access: yesBMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen   +10 more
wiley   +1 more source

Individualised niches: an integrative conceptual framework across behaviour, ecology, and evolution

open access: yesBiological Reviews, EarlyView.
ABSTRACT Individuals differ. While seemingly trivial, this insight has nevertheless led to paradigm shifts, as three key fields of organismal biology have seen marked changes in key concepts over the past few decades. In animal behaviour, it has become increasingly recognised that behavioural differences among individuals can be stable over time and ...
Oliver Krüger   +27 more
wiley   +1 more source

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial–mesenchymal transition and pulmonary niche formation of breast cancer

open access: yesBiological Reviews, EarlyView.
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu   +12 more
wiley   +1 more source

Loss, persistence and reversal of phenotypic traits

open access: yesBiological Reviews, EarlyView.
ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni   +4 more
wiley   +1 more source

Orchard netting impacts on biodiversity leading to cascading effects at the ecosystem level

open access: yesBiological Reviews, EarlyView.
ABSTRACT Agriculture must ensure food production without further compromising the ecosystem functions upon which it depends. Agricultural practices should therefore avoid harming farmland biodiversity, especially of taxa that supply the key ecosystem services (e.g.
Corrado Alessandrini   +13 more
wiley   +1 more source

Enhancing micronutrient bioavailability in wheat grain through organic fertilizer substitution. [PDF]

open access: yesFront Nutr
Wang Y   +10 more
europepmc   +1 more source

Digital Transformation for Eco‐Innovation: Evidence From Agriculture 4.0 Adoption in Wine Firms

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Firms face a fundamental strategic dilemma: how to align digital transformation with environmental sustainability while maintaining competitive advantage. Drawing on the eco‐innovation and green business strategy literature, this paper investigates how Agriculture 4.0 technologies act as enablers of sustainability strategies.
Alessandro Muscio   +2 more
wiley   +1 more source

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