Results 41 to 50 of about 80,743 (315)

Fertilizer and Soil Health in Africa The Role of Fertilizer in Building Soil Health to Sustain Farming and Address Climate Change [PDF]

open access: yes, 2023
Summary Soil health is commonly defined as the ability to generate sufficient crop yields while maintaining the future productive capacity of soils and the ecosystem services soils regulate and deliver.
Cardinae, R.   +25 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Poly-γ-Glutamic Acid-Induced Assemblage of Root Endophytic Microbiota Enhances Disease Resistance in Chrysanthemum Plants

open access: yesAgronomy
Plant microbiota composition changes with the environment and host state, suggesting potential for engineering. However, engineering plant microbiomes is promising but currently undeveloped.
Feng Cui, Lin Zhu, Cheng Zhou
doaj   +1 more source

Preliminary study on the preparation of bio-organic fertilizer from sauce-flavor Baijiu distillers' grains and fertilizer efficiency [PDF]

open access: yesZhongguo niangzao
In order to realize the resource utilization of Baijiu distillers' grains, two kinds of distillers' grains organic fertilizer (treatment group 1 organic fertilizer and treatment group 2 organic fertilizer) were prepared by distillers' grains mixed ...
ZENG Xiang, LI Xiutong, JIANG Youfeng, XIA Xuchun, CHENG Lifangyu, WANG Xiaodan
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Advancing Tandem Organic Solar Cells With Ternary Acceptor Control for High‐Power Modules and Solar‐to‐Ammonia Conversion

open access: yesAdvanced Functional Materials, EarlyView.
Tandem organic solar cells with optimized ternary acceptor engineering achieved a power conversion efficiency of 15.53% and enabled a high‐voltage mini‐module (Voc 6.11 V). Integration into a bias‐free PV‐EC system further demonstrated efficient solar‐to‐ammonia (STA) conversion (97% Faradaic Efficiency, 4± 2% STA efficiency), highlighting scalable ...
Seyeong Song   +11 more
wiley   +1 more source

The relationship between knowledge, attitude, and practice toward organic fertilizer adoption among almond smallholder farmers in Uruzgan, Afghanistan

open access: yes, 2022
Almonds are an important dried fruit and second in the ranking, after raisin and grape, in Afghanistan. The decline in their production is due to low levels of technology adoption, as well as the extreme use and poor timing of inorganic fertilizer ...
Wasil, Abdul Hadi   +2 more
core   +1 more source

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