Results 51 to 60 of about 2,608,216 (300)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Technology of using organic fertilizer in agriculture

ACADEMICIA: An International Multidisciplinary Research Journal, 2022
AbstractThe article presents the data on the technology of using organic and mineral fertilizers in agriculture. About the growing needs of the population for high-quality food products. the main technologies of application of mineral fertilizers.
Jabborov Bakhtiyor Iskandarovich, Jabborova Aziza Bakhtiyorovna   +1 more
openaire   +2 more sources

Narrow-spectrum resource-utilizing bacteria drive the stability of synthetic communities through enhancing metabolic interactions

Nature Communications
The importance of synthetic microbial communities in agriculture is increasingly recognized, yet methods for constructing targeted communities using existing microbial resources remain limited.
Wei Wang, Yanwei Xia, Panpan Zhang, Mengqing Zhu, Shiyi Huang, Xinli Sun, Zhihui Xu, Nan Zhang, Weibing Xun, Qirong Shen, Youzhi Miao, Ruifu Zhang   +11 more
doaj   +1 more source

The Integration of Bio and Organic Fertilizers Improve Plant Growth, Grain Yield, Quality and Metabolism of Hybrid Maize (Zea mays L.)

Agronomy, 2020
Expanding eco-friendly approaches to improve plant growth and crop productivity is of great important for sustainable agriculture. Therefore, a field experiment was carried out at the Faculty of Agriculture Farm, Mansoura University, Egypt during the ...
Canhong Gao, A. El-Sawah, D. Ali, Y. A. Hamoud, Hiba Shaghaleh, M. Sheteiwy   +5 more
semanticscholar   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Cellular ATP redistribution achieved by deleting Tgparp improves lignocellulose utilization of Trichoderma under heat stress

Biotechnology for Biofuels and Bioproducts
Background Thermotolerance is widely acknowledged as a pivotal factor for fungal survival across diverse habitats. Heat stress induces a cascade of disruptions in various life processes, especially in the acquisition of carbon sources, while the ...
Tuo Li, Yang Liu, Han Zhu, Linhua Cao, Yihao Zhou, Dongyang Liu, Qirong Shen   +6 more
doaj   +1 more source

Phages enhance both phytopathogen density control and rhizosphere microbiome suppressiveness

mBio
Bacteriophages, viruses that specifically target plant pathogenic bacteria, have emerged as a promising alternative to traditional agrochemicals. However, it remains unclear how phages should be applied to achieve efficient pathogen biocontrol and to ...
Xiaofang Wang, Shuo Wang, Mingcong Huang, Yilin He, Saisai Guo, Keming Yang, Ningqi Wang, Tianyu Sun, Hongwu Yang, Tianjie Yang, Yangchun Xu, Qirong Shen, Ville-Petri Friman, Zhong Wei   +13 more
doaj   +1 more source

The TgRas1 Gene Affects the Lactose Metabolism of Trichoderma guizhouense NJAU4742

Fermentation, 2023
Trichoderma is one of the fungi commonly used in fermentation engineering. The hydrolytic enzymes secreted by Trichoderma have great economic value.
Jiaxi Miao, Chen Chen, Yajing Gu, Han Zhu, Haiyang Guo, Dongyang Liu, Qirong Shen   +6 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Alternate Nitrogen Amendments for Organic Fertilizers [PDF]

The Scientific World JOURNAL, 2001
The use of compost or manure in agriculture as an organic source of nutrients is common in many tropical, developing countries like Nigeria. One of the drawbacks of such materials is their low nitrogen (N) content (=1% N). Farmers commonly use chemical N fertilizers such as urea, calcium ammonium nitrate (CAN), and NPK formulations to obtain better ...
M.K.C. Sridhar, G.O. Adeoye, O.O. AdeOluwa   +2 more
openaire   +3 more sources