Results 101 to 110 of about 4,386,581 (289)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Trace metal speciation in a wastewater wetland and its bioaccumulation in tilapia Oreochromis niloticus

open access: yesChemical Speciation & Bioavailability, 2018
Trace metal species in the water column of a canal system forming a wetland filled with wastewater were analyzed to determine their correlation with metal accumulation in the gills of locally fished Oreochromis niloticus.
G. Aldana   +5 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Natural organic matter - The relationship between character and treatability [PDF]

open access: yes, 2004
The characterisation and treatment of natural organic matter are becoming more important to the water utilities in the UK and around the world. This paper looks at the relationship between bulk and fractionated organic material and the performance of ...
Bruce Jefferson   +9 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Effect of hydrophilic / hydrophobic fractions of Natural Organic Matter on irreversible fouling of membranes [PDF]

open access: yes, 2009
Natural organic matter (NOM) has been identified as a major factor affecting membrane processes performances, but its impact is difficult to quantify from global parameters such as organic carbon content.
Jefferson, Bruce   +3 more
core   +1 more source

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