Results 41 to 50 of about 87,245 (261)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Anaerobic Organic Matter Uptake by Phosphate-Accumulating Organisms in Activated Sludge
Journal of Japan Society on Water Environment, 2008 An anaerobic aerobic sequencing batch reactor was operated for 185 days using municipal wastewater supplemented with a laundry detergent including LAS and AE to examine the efficiency of acetate uptake and the availability of the surfactants as a potential PHA source of PAOs under exposure to the detergent.
TSUJI, Koji +3 more
openaire +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Frontiers in Earth Science, 2023 The factors controlling the organic matter accumulation in the organic-rich shale of the Lucaogou Formation in the southern Junggar Basin, remain controversial.
Yue Jiao +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Influence of soil macrofauna on soil organic carbon content
Environmental Protection and Natural Resources, 2018 Macrofauna plays a very important role in the functioning of the natural environment. It plays an important role in the decomposition of organic matter by mixing and crushing organic matter in soil.
Szyszko-Podgórska Katarzyna +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Acta Societatis Botanicorum Poloniae, 2015 Scotts pine seedlings were grown in soil cultures with a known content of N and C as well as organic substances. Walter solutions of the following salts: NaNO3, (NH4)2SO4, NH4Cl, NH4NO3, NH4HCO3 were used as a source of nitrogen in particular nutritional
J. Zajączkowska
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Nutrient Accumulation in the Sediment of Silvofishery Ponds in Semarang
Makara Journal of Science, 2017 Information concerning the functionality of mangrove within silvofishery ponds is needed, especially relating to the accumulation rate of organic materials and nutrients.
Endah Dwi Hastuti, Rini Budihastuti
doaj +1 more source