Results 101 to 110 of about 4,128,607 (290)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Distribution and origin of lead in stream sediments from small agricultural catchments draining Miocene molassic deposits (SW France) [PDF]

, 2009
Total Pb concentrations and isotopic composition were determined in stream-bed sediments and bedrock from 29 small agricultural or forested catchments in the Gascogne area (SW France). The contribution of Pb from various natural and anthropogenic sources
Probst, Jean-Luc, N'Guessan, Yao Mathieu, Bur, Thomas, Probst, Anne, A. Probst, T. Bur, J.L. Probst, M. N’guessan   +7 more
core   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Effect of hydrophilic / hydrophobic fractions of Natural Organic Matter on irreversible fouling of membranes [PDF]

, 2009
Natural organic matter (NOM) has been identified as a major factor affecting membrane processes performances, but its impact is difficult to quantify from global parameters such as organic carbon content.
Jefferson, Bruce, Bessiere, Yolaine, Bacchin, Patrice, Goslan, Emma, Y. Bessiere, B. Jefferson, P. Bacchin, E. Goslan   +7 more
core   +1 more source

Organic Matter Enrichment of Black Shale at the Turn of Ordovician-Silurian in the Paleosedimentary Center in Southern Sichuan Basin, Upper Yangtze Area

, 2022
Herein, integrated vertical variation characteristic analysis was conducted by measuring total organic carbon (TOC), major and trace elements in Upper Ordovician-Lower Silurian (Wufeng-Longmaxi formations) black shale in Weiyuan, Luzhou, and Changning ...
Chang R, Huang YZ, Qian C, Cui Y, Guo W, Lin W, Shen WJ（沈伟军）, Li XZ, Han LL, Chao Qian, Wei Lin, Rui Chang, Weijun Shen, Yize Huang, Yue Cui, Wei Guo, Xizhe Li, Lingling Han   +17 more
core   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Study of the trace metal ion influence on the turnover of soil organic matter in cultivated contaminated soils [PDF]

, 2006
The role of metals in the behaviour of soil organic matter (SOM) is not well documented. Therefore, we investigated the influence of metals (Pb, Zn, Cu and Cd) on the dynamic of SOM in contaminated soils where maize (C4 plant) replaced C3 cultures. Three
Quenea, Katelle, Toinen, S., Benedetti, M.F., Bermond, Alain, Benedetti, Marc F., Dumat, Camille, Quenea, K., Bermond, A.   +7 more
core   +1 more source

Sedimentary environmental constraints on organic matter enrichment in the coal-bearing Permian Longtan Formation: a case study from NT1H Well, Central Sichuan Basin, China

Frontiers in Earth Science
The Permian Longtan Formation (burial depth >2000 m) is a major hydrocarbon-producing unit in central Sichuan Basin, China, and an important heterogeneous unconventional gas reservoir.
Yongjun Yao, Yongjun Yao, Xuesong Tian, Xuesong Tian, Xuesong Tian, Maoyao Liu, Maoyao Liu, Yisha Liao, Junfei Peng, Junfei Peng, Junfei Peng, Dongxin Guo, Dongxin Guo, Ye Zhang, Ye Zhang, Yuelei Zhang, Yuelei Zhang, Yuelei Zhang, Cong Tuo, Dishu Chen, Dishu Chen, Dishu Chen, Chaogang Chen, Jinxi Wang, Jinxi Wang, Tingpeng He, Tingpeng He   +26 more
doaj   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source