Results 61 to 70 of about 32,088 (265)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Possibility to estimate trophic status of water body according to its permanganate oxidation value (by the example of the Vishtynetskoye lake, Kaliningrad region)

open access: yesRUDN Journal of Ecology and Life Safety, 2013
The article describes potential sources of organic matters in water of the Vishtynetskoye Lake; based on long-term data temporal fluctuations in easy oxidable organic matters (according to permanganate oxidation value) are analyzed from the point of view
T A Bernikova   +2 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Pore characteristics and evolution of Wufeng–Longmaxi Fms shale gas reservoirs in the basin-margin transition zone of SE Chongqing

open access: yesNatural Gas Industry B, 2019
At present, researches on the pore evolution of shale reservoir and its evolution mechanism are still at such a groping stage that a consensus has not yet reached. Based on core analysis and thermal simulation experiments, the pore types, pore structures
Yuqiao Gao   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Physiological Response of Upland Rice Varieties to Furrow with Organic Matter on Agroforestry System with Kayu Putih (Melaleuca leucadendra L.)

open access: yesCaraka Tani: Journal of Sustainable Agriculture, 2019
Drought is one of the major limitations in dry land cultivation. Drought affects plant physiology processes such as photosynthesis, respiration, mineral and water transportation, and transpiraton, briefly called drought stress.
Puji Lestari Tarigan   +2 more
doaj   +1 more source

The application of biochar and organic matter for proper cultivation on paddy soil

open access: yesJournal of Degraded and Mining Lands Management, 2020
Top soil was rich in nutrients for plant growth. Upper soil loss due to mining is a serious problem. The remaining soil was subordinate land which has poor soil characteristics and low productivity.
Susila Herlambang   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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