Results 121 to 130 of about 791,429 (301)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Optimization of Caffeine Extraction from Various Tea Types Using Dichloromethane as an Organic Solvent

Engineering Proceedings
Caffeine, as 1,3,7-trimethyl-1H-purine-2,6-dione, represents a naturally occurring alkaloid within the methyl xanthine family. Exhibiting bitterness and an odorless state in its pure form, caffeine manifests as needle-like crystals.
Mariam Mir Memon, Muhammad Idress
doaj   +1 more source

A comparison of certain extracting agents for extraction of adenosine triphosphate (ATP) from microorganisms for use in the firefly luciferase ATP assay [PDF]

Firefly luciferase ATP assay is used in clinical and industrial applications, such as determination of urinary infection levels, microbial susceptibility testing, and monitoring of yeast levels in beverages.
Chappelle, E. W., Knust, E. A., Picciolo, G. L.   +2 more
core   +1 more source

Organic Solvent Neurotoxicity [PDF]

Annual Review of Public Health, 1988
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Review of simplified testing method for performance evaluation to assist in the selection of chemical protective gloves

Environmental and Occupational Health Practice
Objective: There is a demand for information on the proper selection, use, and maintenance of impermeable chemical protective gloves to prevent direct skin contact with hazardous substances.
Satoko Iwasawa, Takamasa Aoki, Morinao Fukuoka, Masahiro Miyata, Kunio Shibata, Kento Hoshino, Itsumi Hashimoto, Satoko Suzuki, Noriyuki Yoshioka, Masashi Tsunoda, Hiroyuki Miyauchi   +10 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Yield Optimization for The Extraction of Organic Compounds from Okra Leaves Wastes

Diyala Journal of Engineering Sciences
An important area of research is the extraction of organic chemicals from plants and herbs. Considering the fact that the extracts have numerous commercial and pharmacological uses.
Shaimaa Abod Hussain, Anees A. Khadom, Hameed B. Mahood   +2 more
doaj   +1 more source

Hydrogen bond based noncovalent association in the semi-fluorous solvent perfluorobutyl-methyl ether: Host-host and host-guest association of the host 1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluoro-decyl)-3-pyridin-2-yl-urea [PDF]

, 2013
A fluorous pyridyl-urea, 1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-decyl)-3-pyridin-2-yl-urea, was prepared to act as a host and analyzed by 1H NMR inCD2Cl2 and perfluorobutyl-methyl ether (HFE7100).
McGowan, Candace
core   +1 more source