Results 121 to 130 of about 2,233,551 (298)
Prediction of the pharmaceutical solubility in water and organic solvents via different soft computing models [PDF]
Iranian Journal of Chemical Engineering, 2019 Solubility data of solid in aqueous and different organic solvents are very important physicochemical properties considered in the design of the industrial processes and the theoretical studies.
A. Yousefi, k. movagharnejad
doaj
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Polyetylene Glycols as host solvents: applications to organic synthesis
, 1979 Polyethylene glycols (PEG) are fair solvents for inorganic salts and organic substrates; their use in some organic reactions is ...
A.Manzocchi +5 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The development of sustainable synthetic methodologies represents a central challenge in modern organic chemistry, particularly in light of the environmental impact associated with the large-scale production of fine chemicals and pharmaceuticals.
Luciana Cicco +3 more
core
Enzyme catalysis in organic solvents
, 1990 Enzymes are powerful catalysts with many unique properties. With their high activity and (stereo) selectivity they have great potential for many applications as catalysts in organic synthesis.
Mooldijk, R.J. (author)
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source