Results 91 to 100 of about 528,498 (289)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Characterization of Humic Substance Extracted from Andisols, Spodosols, Peat, and Lignite

Sains Tanah: Journal of Soil Science and Agroclimatology, 2018
Soil and other materials with high C-organic content are potential natural sources of humic substances. Until now the differences in the characteristics of such humic substances that are extracted from different sources have not been widely studied. Thus,
Eka Rahmi, Suwardi Suwardi, Basuki Sumawinata   +2 more
doaj   +1 more source

UK and EU policy for approval of pesticides suitable for organic systems: Implications for Wales [PDF]

, 2004
This study was commissioned by the Welsh Assembly Government (WAG) to review the pesticide approval system in the UK and Europe as far as it affects the use of substances and techniques for crop protection by organic producers in Wales. WAG considers it
Bradshaw, N J, Buffin, D, Hitchings, R, Little, A J, Stopes, C J   +4 more
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Synthesis, characterization, antimicrobial and antioxidant activity of 2- (2′-hydroxyphenyl) -1,3,4-oxadiazolyl-5-amino acid derivatives

Journal of Saudi Chemical Society
The synthesis and biological assessment of 2,5-disubstituted-1,3,4-oxadiazoles derivatives from amino acids as new potential antibacterial and antioxidant agents have been reported. The structures of the new synthesized compounds were characterized based
Mouna Souad Abbassi, Talal Lahreche, Khaled Briki, Mokhtar Boualem Lahrech, Adil Ali Othman, Ahmed M. Elissawy, Abdel Nasser B. Singab   +6 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Synthesis and Cytotoxic Activity of a New Family of α-Hydroxyphosphonates with the Benzothiophene Scaffold

Pharmaceuticals
Background: α-Hydroxyphosphonates, one of the most prominent classes of phosphonates, remain of utmost importance because of their potential and real biological activity as pharmaceutical or pesticide agents. The effect is the consequence of their enzyme
Mátyás Milen, Tamás Miklós John, Anna Sára Kis, Zsófia Garádi, Zsuzsanna Szalai, Angéla Takács, László Kőhidai, Konstantin Karaghiosoff, György Keglevich   +8 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Interrogating the Transient Selectivity of Bacterial Chemotaxis-Driven Affinity and Accumulation of Carbonaceous Substances via Raman Microspectroscopy

Frontiers in Microbiology, 2019
Carbonaceous substances are fundamental organic nutrients for microbial metabolism and catabolism in natural habitats. Microbial abilities to sense, accumulate, and utilize organic carbonaceous substances in the complex nutrient environment are important
Hanbing Li, Hanbing Li, Francis L. Martin, Kevin C. Jones, Dayi Zhang   +4 more
doaj   +1 more source

Degradation behaviour of potassium K-phosphite in apple trees [PDF]

, 2008
Although potassium phosphite is not registered for organic fruit production in Europe, it has long been regarded as a potential alternative to sulphur- and copper-containing fungicides.
Casera, Claudio, Kelderer, Markus, Matteazzi, Aldo   +2 more
core