Results 111 to 120 of about 2,067,945 (289)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

The Organic Market in Europe 2012 [PDF]

open access: yes, 2014
In 2012, the organic market continued to grow in the European Union, even though some countries were still affected by the economic crisis, leading to stagnation or even decline.
Schlatter, Bernhard   +3 more
core   +1 more source

Integrated Mixotrophic Cultivation Strategy for Limnospira (Spirulina) Platensis using Vinegar Wastewater: Productivity Enhancement through Controlled Organic Supplementation and Salinity Optimization

open access: yesChemical Engineering Transactions
Agro-industrial wastewaters rich in organic compounds represent both an environmental liability and a potential resource for sustainable bioprocesses. This study evaluated a cultivation strategy for Limnospira (Spirulina) platensis based on controlled ...
Luca Usai   +5 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

The organics iceberg and the tyranny of organic certification [PDF]

open access: yes, 2013
The existence of an ‘organics iceberg’ is a hypothesis rather than a fact. Nevertheless, reports in The World of Organic Agriculture that there are 37,245,686 certified organic hectares worldwide and that this accounts for 0.86% of global agriculture are
Paull, John
core   +1 more source

Microalgae as a selenium vehicle for nutrition: a review

open access: yesDiscover Food
Selenium (Se) is essential for human and animal nutrition, playing a key role in antioxidant and immune functions. Organic Se is better for supplementation because it is more efficiently assimilated and less toxic than its inorganic form.
Rita Pires   +7 more
doaj   +1 more source

Evaluation of Fish Biosolids as a Fertilizer for Organic Tomato Transplant Production

open access: yesHorticulturae
Interest among consumers in the availability of organically produced fruits and vegetables is increasing. Seafood demand is increasingly being met by fish raised using aquaculture methods that provide fish excretory products that can meet organic ...
Cicely Schembri   +4 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

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