Results 81 to 90 of about 2,001 (290)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcending the Surface: The body as a Rhetorical and Ideological Enunciator in the Documentary Noticias.

Catedral Tomada: Revista de Crítica Literaria Latinoamericana, 2018
The text raises a critical interpretation about the representation of the body in the documentary Noticias (2009) of the Chilean directors Bettina Perut and Ivan Ossnovikof.
Vladimir Silva Oyaneder
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

SMART TOURISM DESTINATION & CULTURAL HERITAGE: A NEW UNEXPLORER SECTOR IN SMART CITIES DEVELOP [PDF]

, 2017
Las ciudades inteligentes están habilitadas para la creación y desarrollo de ecosistemas para nuevos servicios más personalizados en dominios como el turismo, la promoción del patrimonio cultural y la participación activa, una línea de actuación con ...
Jara, Antonio Jesús, Gómez Oliva, Andrea, Parra Meroño, María Concepción, Server Gómez, Matilde   +3 more
core   +1 more source

Deconstructing Grotowski

Revista Brasileira de Estudos da Presença, 2013
This article is a structural, thematic and methodological analysis of the book Palavras Praticadas: o percurso artístico de Jerzy Grotowski, 1959 –1974, by Tatiana Motta Lima (2012).
Dorys Faria Calvert
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

GRAMSCI E A RELAÇÃO ORGÂNICA ENTRE CULTURA E VIDA SOCIAL | Gramsci and the organic relationship between culture and social life

Trabalho & Educação, 2018
The present article addresses a particular aspect of the struggle for the conquest of hegemony in Antonio Gramsci (1891-1937), that is, the cultural aspect.
João Batista Favaretto
doaj  

Classification criteria of antiphospholipid syndrome ACR/EULAR 2023 and comments on them

Научно-практическая ревматология
Many rheumatic diseases are a model of human pathology disease. These are inflammatory rheumatic diseases, autoinflammatory and autoimmune diseases. Antiphospholipid syndrome (APS) is a model of antibody-induced thrombosis or acquired thrombophilia.
T. M. Reshetnyak
doaj   +1 more source