Results 61 to 70 of about 848 (256)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Scouting the Desert of the Real: Avant-Gardism of the Avant-Pop
ELOPE, 2010 The paper examines the legacy of the European historical Avant-Gardes from the perspective of the shift of paradigms immanent in the formation of the Postmodern epoch.
Mojca Krevel
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Catedral Tomada: Revista de Crítica Literaria Latinoamericana, 2018 The text raises a critical interpretation about the representation of the body in the documentary Noticias (2009) of the Chilean directors Bettina Perut and Ivan Ossnovikof.
Vladimir Silva Oyaneder
doaj +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Cadernos de Letras da UFF, 2012 Organizers and program committee for the Intelligent Narrative Technologies 2012 AIIDE ...
openaire +10 more sources
Revista Brasileira de Estudos da Presença, 2013 This article is a structural, thematic and methodological analysis of the book Palavras Praticadas: o percurso artístico de Jerzy Grotowski, 1959 –1974, by Tatiana Motta Lima (2012).
Dorys Faria Calvert
doaj
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Classification criteria of antiphospholipid syndrome ACR/EULAR 2023 and comments on them
Научно-практическая ревматологияMany rheumatic diseases are a model of human pathology disease. These are inflammatory rheumatic diseases, autoinflammatory and autoimmune diseases. Antiphospholipid syndrome (APS) is a model of antibody-induced thrombosis or acquired thrombophilia.
T. M. Reshetnyak
doaj +1 more source