Results 61 to 70 of about 2,001 (290)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Between cinema and theatre : transparency and organicity in acting [PDF]
Orientador: Sílvia Maria GeraldiDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de ArtesResumo: A presente pesquisa abordou as noções de transparência e organicidade como qualidades do trabalho do ator no cinema e no teatro ...
Alckmin Neto, José Geraldo Rodrigues de, 1984-
core
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
IN SEARCH OF RELIABLE KNOWLEDGE: REFLECTION IN THE LIGHT OF THE THINKING OF JOHN ZIMAN
A reflective study, based on content analysis, which aimed to widen discussion among Nursing researchers on the subject of the challenges of scientific literature production, to attain a degree of knowledge which is reliable or nearly so, in the light of
Elizabeth Teixeira +1 more
doaj +1 more source
Cerebral calcifications and schizophreniform disorder
OBJECTIVES: Discuss pathophysiological aspects of cerebral calcifications (CC) and highlight its importance related to the occurrence of neuropsychiatric syndromes. METHOD: Single case report.
Leonardo Fernandez Meyer +4 more
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Summarization: The city of Athens, economic, political and administrative capital of Greece since 1833, has been developed upon ancient settlements of 2000 years and more.
Tsouderos, Giannēs Emmanouēl(http://viaf.org/viaf/21057226) +3 more
core
Validation of the Tactual Performance Test as an Organicity Screening Device [PDF]
Organicity screening devices are those psychometric tests used to detect brain dysfunction during the initial assessment. The characteristics of such tests were listed and ones currently being used were reviewed.
Lippold, Stephen C.
core
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source

