Results 51 to 60 of about 2,001 (290)
Validity of the Hand Test for Diagnosing Organicity in a Clinical Setting
, 1983 When validated against a clinical sample, the Hand Test was able to differentiate between 50 brain-damaged and 50 functionally disturbed individuals with 69% accuracy.
Edwin E. Wagner, Mary K. T. McCormick
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Ecological imperatives in contemporary Hungarian poetry
Hungarian Studies Yearbook, 2023 The study reviews from an ecopoetic point of view the tendencies in Hungarian poetry of recent years that emphasise the biopoetic aspects of existence. László Lázár Lövétei’s eclogues, for example, renew the discourse from the perspective of the ancient ...
Csehy Zoltán
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
SCREENING FOR ORGANICITY: A COMPARISON OF TWO NEUROPSYCHOLOGICAL PROCEDURES
, 1987 This study compares the Short Portable Mental Status Questionnaire (SPMSQ) with the Bender Gestalt Test (BGT) in screening for organicity among psychiatric patients.
CHAPMAN, BENJAMIN C
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Frontal lobe meningioma presenting as mania
Archives of Mental Health, 2017 Frontal meningiomas may present with psychological symptoms without any neurological signs. Diagnosis of frontal lobe tumours are often delayed due to the insidious nature of the symptoms and psychiatric symptoms being the initial presentation rather ...
S Mithun, Divya Hegde, Priya Sreedaran
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Cerebellar stroke-manifesting as mania
Indian Journal of Psychological Medicine, 2014 Secondary mania resulting from cerebral Cortex are described commonly. But secondary mania produced by cerebellar lesions are relatively uncommon. This case report describes a patient who developed cerebellar stoke and manic features simultaneously.
Venkatesan Jagadesan +2 more
doaj +1 more source