Community Implementation of a Clinician and Caregiver Co-Led Programme to Promote the Wellbeing of Family Caregivers of Individuals With Intellectual and Developmental Disabilities. [PDF]
Selick A +11 more
europepmc +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Mental Health Service Preparedness during a Pandemic: A Delphi Study in Slovenia. [PDF]
Selak Š +3 more
europepmc +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
'We Feel Invisible a Lot of the Time': Insights Into the Roles of Alcohol and Other Drug Lived and Living Experience Workers. [PDF]
Roxburgh AD +3 more
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Global Incidence of Appendectomy: A Population-Based Study of the Organisation for Economic Co-operation and Development. [PDF]
Buie EM +9 more
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
D’une coopération verticale à une planification coopérative des actions
Sylvia Pelayo
doaj +1 more source
From EM to AI: Multiscale imaging of the secretory pathway with insights from plant cells. [PDF]
Pain C, Farley E.
europepmc +1 more source

