Results 101 to 110 of about 121,630 (296)

Donations of consumables and surgical instruments: how to ensure you really benefit

open access: yesCommunity Eye Health Journal, 2011
Advice on how to ensure that your unit benefits the most from donated medicines, medical consumables, and surgical instruments.
Ismael Cordero
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Kommunikation vid förändringsarbete. Hur kommunikation kring implementering av en statlig reform påverkat de anställdas benägenhet att acceptera förändring [PDF]

open access: yes, 2018
It is important for organizations to be able to adapt to change. By implementing new changes they are able to stay relevant and prosper. A critical factor when doing this is the ability to accurately communicate change to the employees. By doing so the
Selén, Johanna, Bertilsson, Nelly
core   +1 more source

Administration in land management – the organisation and scope of new local bodies [PDF]

open access: yesUrbani Izziv, 1994
In the article the temporary organisation in land management and administration in 21 new communes is described, commented and critically analysed. Proposals for a rationalised system are given.
Breda Ogorelec
doaj  

Process Management in Public Management of a Transition Country: Case Study of Bosnia and Herzegovina

open access: yesBusiness Systems Research, 2013
Background: New methods, means and approaches for increasing the efficiency of public administration are constantly being discovered. This paper considers the possibility of applying a new form of organisation-known as the process organisation structure ...
Salkić Ismet, Bošnjović Jasna
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Administration centrale. — Organisation du Secrétariat général

open access: yes
Bourbeau Olivier. Administration centrale. — Organisation du Secrétariat général. In: Bulletin administratif de l'instruction publique. Tome 12 n°223, 1869.
Bourbeau, Olivier
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Home - About - Disclaimer - Privacy