Results 81 to 90 of about 121,630 (296)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

E-Administration as a Way of Increasing the Managerial Capacity in Public Sector [PDF]

open access: yes
This paper deals with a developing concept, that of public sector reform, and explores it within the boundaries of e-administration practices. International competition and internal raising expectations have lead governments across the world to ...
Iancu, Diana Camelia, Matei, Ani
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

A case study of Whangaparaoa College: a transformative learning organisation in the making? [PDF]

open access: yes, 2009
The concept of a learning organisation is relatively new to schools and educational institutions in New Zealand. Understanding educational institutions as learning organisations can enable institutions to meet the demands of an ever changing context.
Krishnamoorthy, Rajalakshmi
core  

Nursing personnel administration within a hospital [PDF]

open access: yes, 1980
Masters in Public Administration - MPAThe nurse qualified in the area of administration occupies a position with immense scope and potential in the profession and in society. The task of senior nursing management is a matter of balancing and reconciling
Thompson, Rosalie A.E
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

CPD - The learning preferenccs of general practioners

open access: yesSouth African Family Practice, 2003
General Practitioners need to stay up to date and to maintain professional competence. The Health Professions Council of SA has introduced a mandatory recertification system starting in 1999.
I. van den Berg, M.R. de Villiers
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Current problems of educational administration in the state of Kuwait [PDF]

open access: yes, 1987
This research is an inquiry into the current problems and difficulties of educational administration in Kuwait. The study comprises eight chapters. The introduction defines the scope and purpose of the study and the methodology employed.
Al .Musailim, Muhammad Yousef
core  

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