Results 101 to 110 of about 43,704 (294)

The Psychodynamics of Top Teams and the Impact on Strategic Organisational Learning: Three Case Studies in the Public Sector [PDF]

, 1998
The growing literature on organisational change, organisational learning and the role of the top team prompted the question: what is the relationship between top teams and organisational leaming?
Jarrett, Michael, Jarrett, M.G.
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Work–family balance of Indian women software professionals: A qualitative study

IIMB Management Review, 2011
One of the significant changes witnessed in the labour markets in India has been the entry of women IT professionals in the rapidly growing software services sector.
Reimara Valk, Vasanthi Srinivasan
doaj   +1 more source

Organisational behaviour: core concepts and applications, Australia

, 2019
Organisational Behaviour: Core Concepts and Applications presents Organisational Behaviour in print and an interactive digital format and is an ideal text for students interested in management or human resources. The information is offered in a clear and
Fromholtz, Michele, McKeown, Tui, Zeffane, Rachid, Factor, Aharon, Morrison, Rachel R., Wood, Jack, Wiesner, Retha   +6 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Organisational, group and individual lean health stakeholders: adapting lean thinking's customer focus to health services settings

, 2010
BACKGROUND: Adaptations of Lean manufacturing process techniques appear more frequently in health services than any other public service context. The core of Lean manufacturing philosophy is to make value (as perceived by the customer) the key concern of
Reed, Nick, Fitzgerald, Anneke, Hayes, Kathryn J. (R12313)   +2 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Employee grievance research through an organisational behaviour framework

, 2010
Purpose of the research/paper: The complexities surrounding grievance activity in the workplace makes a single theoretical explanation for the entire process an unlikely achievement.
Southey, Kim
core  

Self- or rule-based governance: Analysis of choice-making behaviour [PDF]

, 2010
Purpose - This study seeks to propose self-governance in organisations based on choice-making behaviour. Design/methodology/approach - The paper examines selected literature on the behaviour of choice, moving from the individual as the unit of ...
Mostovicz, E Isaac, Kakabadse, Nada K, Nada K. Kakabadse, Mostovicz, E. Issac, Kakabadse, Andrew P., Kakabadse, Andrew P, Kakabadse, Nada K., Andrew P. Kakabadse, E. Isaac Mostovicz   +8 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source