Results 101 to 110 of about 368,467 (295)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Digital accessibility: Challenges and opportunities

open access: yesIIMB Management Review, 2019
This round table is focussed on outlining barriers to digital accessibility, solutions, and possible next steps to ensuring digital accessibility.
Mukta Kulkarni
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Work–family balance of Indian women software professionals: A qualitative study

open access: yesIIMB Management Review, 2011
One of the significant changes witnessed in the labour markets in India has been the entry of women IT professionals in the rapidly growing software services sector.
Reimara Valk, Vasanthi Srinivasan
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

CONSIDERATIONS ON THE BANKING PRODUCTS AND SERVICES IN THE GLOBALISATION CONDITIONS [PDF]

open access: yes
The changes occurred in the banking marketing in our country have their origin, firstly, in the changes of the organisational culture which has evolved in the last ten years from the bureaucratic behaviour, categorised excessively, to a specific ...
Avram Costin Daniel, Avram Veronel
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

A future for organisational behaviour?

open access: yesEuropean Business Review, 2009
PurposeThe purpose of this paper is to raise and critically analyse controversial issues facing the future directions of the academic discipline organisational behaviour (OB).Design/methodology/approachSpecifically, the commercial benefits for basic and applied OB research conducted by academics are considered.
Hosie, Peter J., Smith, Roger C.
openaire   +4 more sources

Empirical Evidence for the Relation between Customer Satisfaction and Business Performance [PDF]

open access: yes
This paper focuses on the analysis of empirical data on customer satisfaction and the relationship with hard organisational performance data. The organisation is a Flexcompany with its headquarters in The Netherlands, but also operating in other ...
Boselie, J.P.E.F.   +2 more
core   +1 more source

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