Results 61 to 70 of about 519,146 (302)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Aportes teórico-conceptuales acerca del cambio organizacional de la industria cafetera colombiana

Suma de Negocios, 2017
The transformation of the coffee sector can be analysed under the perspective of change in organisational fields that enables failures that generate destabilisation to be signalled and anticipated. This article analyses the way how change is developed in
Cristian A. Yepes Lugo
doaj   +1 more source

Local governments' decade of organisational change to promote child health and wellbeing: a Western Australian qualitative study

Australian and New Zealand Journal of Public Health, 2021
Objective: We aim to reflect on the introduction of risk‐based approaches to public health, driven by legislation outlining the expected local government public health functions and roles by identifying factors that most influenced organisational change ...
Melissa Stoneham, Melinda Edmunds, Christina Pollard   +2 more
doaj   +1 more source

Design and Implementation of Small Multiples Matrix-based Visualisation to Monitor and Compare Email Socio-organisational Relationships [PDF]

, 2018
One of the fundamental organisational questions is how organisations identify anomalies, monitor and compare email communications between staff-staff or staff-clients or staff-customers relationships on a daily basis.
Fadahunsi, O, Sathiyanarayanan, M., Turkay, C.   +2 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Sustaining effective literacy practices over time in secondary schools: School organisational and change issues [PDF]

, 2007
The effective, sustained implementation of literacy across the curriculum in secondary schools is still a relatively rare phenomenon. This is because such an approach to literacy requires secondary schools to undergo extensive and complex processes of ...
May, Stephen
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Application of ONA in Change Management – Empirical Research in Energy Industry

Problemy Zarządzania, 2016
The article aims to examine the empirical change implementation process from the resource-based point of view and from the dynamic-based point of view, exploiting the organisational network analysis as the main method.
Anna Szarek
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source