Results 81 to 90 of about 416,711 (288)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Organisational and Strategic Communication: Editorial Introduction

Comunicação e Sociedade, 2014
The study of communication in organisations – in a broad sense, and without source scientific field restrictions (which included traditional research into Organisational Communication, Public Relations, Institutional Communication, Internal Communication,
Teresa Ruão, Margarida Kunsch
doaj   +1 more source

Identity studies: Multiple perspectives and implications for corporate-level marketing [PDF]

, 2007
Purpose – Provides a comprehensive review of the identity literature drawing on perspectives from marketing (corporate identity concept) and organisational behaviour (organisational identity) so as to provide an up-to –date overview of identity ...
Balmer, JMT, He, HW
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Funding community organising: diversifying sources, democratising civil society [PDF]

, 2019
This chapter recognises the variety, complexity, and contested politics of community organising — a practice that ranges from consensus-based community building to more conflict-oriented grassroots organising confronting oppression. It focuses on the need for movement-like organising for economic and social justice at the local level and beyond.
Fisher, Robert, Balazard, Hélène
openaire   +3 more sources

Institutionalising ethical cultures: an investigation of formal organisational approaches [PDF]

, 2006
This thesis examined the institutionalisation of ethics within Australian organisations. A particular focus is the role of the strategic apex, or executive level of the organisation, in establishing the environment in which an ethical culture can develop.
Segon, Michael John
core   +1 more source

Healthy universities: an example of a whole-system health-promoting setting [PDF]

, 2016
The health-promoting settings approach is well established in health promotion, with organisational settings being understood as complex systems able to support human wellbeing and flourishing. Despite the reach and evident importance of higher education
Bauer G, Brennan J, Dooris M, Dooris M, Higher Education Statistics Agency (HESA), Jane Wills, Joanne Newton, Mark Dooris, Simons H, Stake R, Whitelaw S, World Health Organization (WHO), World Health Organization (WHO), Yin R   +13 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Social Media – the new challenge for PR measurement and evaluation [PDF]

, 2012
In the five years since Paul Noble and I wrote the second edition of our book, Evaluating Public Relations, the biggest change in the field has been the rapid emergence of social media in media relations and organisational communication.
Watson, Tom
core  

Modelling Organisational Factors Influencing Sustainable Development Implementation Performance in Higher Education Institutions: An Interpretative Structural Modelling (ISM) Approach [PDF]

, 2019
open access articleGlobally, higher education institutions (HEIs) have continued to record varied sustainable development (SD) implementation performances. This variance has been attributed to the presence of certain organisational factors.
Abuzeinab, Amal, Awuzie, Bankole Osita
core   +2 more sources