Results 121 to 130 of about 130,600,341 (310)

Draft Financial Rules and Regulations of the Organization of African Unity

open access: yes, 1978
This report contains the draft financial rules and regulations to be applied to the budget and financial management of the Organization of African Unity and all its ...
Organization of African Unity
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Quality of Local Rice Genotypes and Their Improvement With Urea and Fermented Rice Husk Ash

open access: yesAdvances in Agriculture
The quality and nutritional value of rice (Oryza sativa L.) are important for its economic value and for addressing malnutrition in developing countries.
Nurhayati Nurhayati   +10 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Haplotype diversity of 17 Y-STR in the Iranian population

open access: yesBMC Genomics
The current study aimed to evaluate Y chromosome haplotypes obtained from 1353 unrelated Iranian males using the AmpFlSTRTM YfilerTM kit; 1353 out of the 1353 identified haplotypes were unique. The haplotype diversity (HD) and discriminating capacity (DC)
Mohammad Reza Eskandarion   +22 more
doaj   +1 more source

Application for Subvention Submitted by the Pan-African Women’s Organization (PAWO)

open access: yes, 1982
Council of Ministers Thirty-eighth Ordinary Session Addis Ababa, Ethiopia 22 February - 1 March 1982This report considers the application for Subvention from the Pan-African Women’s Organization (PAWO) to the Organization of African Unity as well as the ...
Organization of African Unity
core  

Request for Subvention by the Pan-African Women's Organization [PDF]

open access: yes, 1985
Council of Ministers Forty-Second Ordinary Session July 1985 Addis Ababa, EthiopiaThis report presents the request for subvention from the OAU by the Pan-African Women's Organization for the 1986 financial year, with highlights on its budgetary ...
Organization of African Unity
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy