Results 91 to 100 of about 235,010 (211)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Supplementum 175: 15th Wonca Europe Conference (Basel, Switzerland, September 16-19, 2009)
Swiss Medical Weekly, 2009 World Organization of Family Doctors (Wonca)
doaj +1 more source
BİREYSEL AYRILIKLAR ve TOPLUMSAL DEZAVANTAJLAR ÇERÇEVESİNDE İŞYERİNDE PSİKOLOJİK TACİZ: MOBBİNG
Mehmet Akif Ersoy Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi, 2015 Çalışma hayatı, kişinin rutin yaşamının bir parçası olmakla birlikte, özellikle Türkiye gibi toplumlarda büyük bir parçası olmaktan ötürü, bireyi geniş çaplı bir boyutta etkileyen ve belirleyen nitelikler göstermektedir.
Meriç Pehlivan
doaj
Cloud Versus Void Chord Length Distributions (LvL) as a Measure for Cloud Field Organization
Geophysical Research LettersCloud organization impacts the radiative effects and precipitation patterns of the cloud field. Deviating from randomness, clouds exhibit either clustering or a regular grid structure, characterized by the spacing between clouds and the cloud size ...
Ilan Koren +3 more
doaj +1 more source
Proceedings of the AAAI Conference on Artificial Intelligence and Interactive Digital Entertainment, 2013 List of organizers of the Musical Metacreation 2014 AIIDE Workshop.
openaire +3 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source