Results 121 to 130 of about 2,776,402 (256)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Aspectos bélicos de la Guerra de la Independencia
Cuadernos Dieciochistas, 2009 RESUMEN: El autor trata de exponer los aspectos más relevantes de esta dilatada guerra, tanto desde el punto de vista polemológico, como desde el de la profesión militar, este último concretamente orientado hacia las disciplinas básicas que debe estudiar
José María BLANCO NÚÑEZ
doaj
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
World Health Organization in Kazakhstan
, 2018 6 p.The World Health Organization (WHO) is the global authority on public health within the United Nations. Founded in 1948, we collaborate with the governments of 194 Member States to ensure the highest attainable level of health for all.
World Health Organization. Regional Office for Europe
core
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
BİREYSEL AYRILIKLAR ve TOPLUMSAL DEZAVANTAJLAR ÇERÇEVESİNDE İŞYERİNDE PSİKOLOJİK TACİZ: MOBBİNG
Mehmet Akif Ersoy Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi, 2015 Çalışma hayatı, kişinin rutin yaşamının bir parçası olmakla birlikte, özellikle Türkiye gibi toplumlarda büyük bir parçası olmaktan ötürü, bireyi geniş çaplı bir boyutta etkileyen ve belirleyen nitelikler göstermektedir.
Meriç Pehlivan
doaj
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Early onset of seasonal influenza and emerging RSV activity: Implications for health systems
Revista Panamericana de Salud PúblicaPan American Health Organization
doaj +1 more source