Results 111 to 120 of about 11,857,015 (307)

Computer Games and Organization Studies

open access: yes, 2016
Computer games and organizations are becoming increasingly interwoven in the 21st century. Sophisticated computer games connected by networks are turning into spaces for organizing.
Harviainen, J. Tuomas   +3 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

WHO management response to preventing and responding to sexual exploitation, abuse and harassment: report 2021- 2022

open access: yes, 2023
vi, 27 p.This report summarizes the World Health Organization’s management response during 2021–2022 to preventing and responding to sexual exploitation, abuse and harassment (SEAH), following the recommendations of the Independent Commission established
World Health Organization
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Scoping Ethical AI in Working Life: Lessons for the Nordic Model

open access: yesNordic Journal of Working Life Studies
The Nordic working life is characterized by high union density, flat organizations, and trust. In this context, ethical artificial intelligence (AI) implementation requires dialogue and collective decision-making between employers and employees.
Christoffer Larsson   +2 more
doaj   +1 more source

Enabling Business Model Change: Evidence from High-Technology Firms

open access: yesJournal of Entrepreneurship, Management and Innovation, 2015
Companies today face volatie environments, short product life cycles, and changing customer requirements, which is especially the case in high-technology filds.
Christiana Müller, Stefan Vorbach
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

FUNCTIONAL MANAGER SUBSYSTEM OF THE ORGANIZATION END MANAGEMENT BY BJECTIVES OF THE ORGANIZATION [PDF]

open access: yes
Continuous process of asset management and communication between higher and subordinate employee evaluation method that allows determining, measuring, monitoring and performance objectives and eliminating deviaţionismului functional organizations ...
Munteanu Stolojanu Victoria-Ileana
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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