Results 91 to 100 of about 730,203 (311)

Organization and administration of information networks : a comparative study of the United States and China

open access: yes, 2000
The progress of combining computer with communication technology has been making the industrial boundary of computer, telecom, and ente1tainment to disappear. Information networks are becoming the most important infrastructure for human society.
Yi, Ming
core  

Consideration of applications for subventions submitted by the association of African Universities [PDF]

open access: yes, 1975
Council of Ministers Twenty-Fourth Ordinary Session Addis-Ababa, February 1975This request is presented by the Association of African Universities to the Secretary-General of the Organization of African Unity requesting for Grant of 100,000 US dollars ...
Organization of African Unity
core  

Shaping the Classroom: How Job Crafting and LMX Can Drive Teacher Performance and Well-Being

open access: yesEducation Sciences
The teaching profession plays a central role in shaping educational quality and student development, yet it is increasingly characterized by high job demands and increasing pressures.
Charlotte Malengier   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Jonesboro Metropolitan Planning Organization 2030 Long Range Transportation Plan

open access: yes, 2005
95 pages. Prepared by Jonesboro MPO in cooperation with Arkansas State Highway and Transportation Department, United States Department of Transportation, Federal Highway Administration, Federal Transit ...
Jonesboro Metropolitan Planning Organization
core  

Children's Medicines in Tanzania: A National Survey of Administration Practices and Preferences. [PDF]

open access: yes, 2013
The dearth of age-appropriate formulations of many medicines for children poses a major challenge to pediatric therapeutic practice, adherence, and health care delivery worldwide.
Gary J Noel   +44 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Complexity Theory and Public Administration: What's New?

open access: yes, 2008
Increasing attention is being paid to the application of complex systems theories in the social sciences. Although this trend is less prominent in the field of public administration, some examples of the use of complexity theory in research in this ...
Erik-Hans Klijn, Klijn, Erik Hans
core   +1 more source

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