Results 81 to 90 of about 826,626 (298)

Designing a Strategic Renewal Model for Healthy Aging Based on Organizing Public Sports for the Elderly in Urban Parks [PDF]

مجله علوم پزشکی صدرا
Introduction: The global population is aging, with the proportion of elderly individuals increasing with each census. Therefore, investigating strategies to improve the health and well-being of this demographic is imperative. This study aimed to design a
Amir Moradi Niknam, Mohsen Davoodi, Rouzbeh Darvishi, Moein Bani Asadi   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Journey to 2030 : transportation plan of the Boston region metropolitan planning organization. [PDF]

3C PL Contract #48696MA-80-0001JOURNEY to 2030, the Transportation Plan of the Boston Region Metropolitan Planning Organization (referred to as the Plan), is the long-range, comprehensive transportation planning document for the Boston region. The region
Metropolitan Planning Organization (Mass.). Central Transportation Planning Staff
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

HLAD 745 Organization Theories in Health Administration

, 1997
Course syllabus for HLAD 745 Organization Theories in Health Administration Course description: The student will be exposed to organizational theories and behavior relevant and unique to effective administration of health care institutions.
Wentz, Walter J.
core   +1 more source

O Manicômio Judiciário: saúde ou justiça?

Revista de Saúde Pública
O Manicômio Judiciário, por ser um hospital-presídio, pode estar subordinado tanto à Secretaria da Saúde como à Justiça. Como elementos de análise dessa decisão, são apresentadas comparações estruturais e de recursos humanos entre o Manicômio Judiciário ...
Evelin Naked de Castro Sá
doaj  

Organization and administration of information networks : a comparative study of the United States and China [PDF]

, 2000
The progress of combining computer with communication technology has been making the industrial boundary of computer, telecom, and ente1tainment to disappear. Information networks are becoming the most important infrastructure for human society.
Yi, Ming
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source