Results 61 to 70 of about 670,285 (262)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A PRODUÇÃO CIENTÍFICA SOBRE GERENCIAMENTO EM ENFERMAGEM HOSPITALAR: UMA PESQUISA BIBLIOGRÁFICA
Cogitare Enfermagem, 2009 Pesquisa bibliográfica com objetivo de identificar e analisar a produção científica sobre gerenciamento em enfermagem, em hospitais, no Sistema Único de Saúde, no período de 1988-2007.
Marina Massaro +1 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Cadernos de Saúde PúblicaEsta investigación describe el nivel de implementación del Programa de Seguridad y Salud en el Trabajo en empresas colombianas, ubicadas en el departamento de Antioquia, y los factores que inciden en ello.
Ninfa Del Carmen Vega-Monsalve
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
O Manicômio Judiciário: saúde ou justiça?
Revista de Saúde PúblicaO Manicômio Judiciário, por ser um hospital-presídio, pode estar subordinado tanto à Secretaria da Saúde como à Justiça. Como elementos de análise dessa decisão, são apresentadas comparações estruturais e de recursos humanos entre o Manicômio Judiciário ...
Evelin Naked de Castro Sá
doaj
Revista Latino-Americana de Enfermagem, 2008 This study was carried out at a teaching hospital in Southern Brazil, which adopted a management model that provoked the dismantling of the nursing service and the disbandment of nursing professionals.
Elizabeth Bernardino +1 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Designing a Strategic Renewal Model for Healthy Aging Based on Organizing Public Sports for the Elderly in Urban Parks [PDF]
مجله علوم پزشکی صدراIntroduction: The global population is aging, with the proportion of elderly individuals increasing with each census. Therefore, investigating strategies to improve the health and well-being of this demographic is imperative. This study aimed to design a
Amir Moradi Niknam +3 more
doaj +1 more source