Results 51 to 60 of about 730,203 (311)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Public policy observatories in the Americas: A guide for their design and implementation in our public administrations [PDF]

open access: yes, 2015
Public policy observatories are an initiative that some public administrations in the US and Europe have implemented to manage knowledge. The use of observatories enables public administrators to have greater information to design, develop, implement ...
Organization of American States
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

MANAGEMENT OF TEACHING AT A NURSING COLLEGE - PERCEPTIONS OF MANAGERS [PDF]

open access: yesRevista Gestão & Saúde, 2013
The objective of this research is to describe, from the perspective of managers, how the management of teaching happens. It’s a exploratory study, conducted in in a Public University in Midwest Region. Subjects were occupants of the positions of Director,
Leonara Raddai Gunther de Campos   +1 more
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Journey to 2030 : transportation plan of the Boston region metropolitan planning organization. [PDF]

open access: yes
3C PL Contract #48696MA-80-0001JOURNEY to 2030, the Transportation Plan of the Boston Region Metropolitan Planning Organization (referred to as the Plan), is the long-range, comprehensive transportation planning document for the Boston region. The region
Metropolitan Planning Organization (Mass.). Central Transportation Planning Staff
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Bonneville Power Administration 1991 Annual Report.

open access: yes, 1992
Congress enacted the Bonneville Project Act in 1937, creating the Bonneville Power Administration to market and transmit the power produced by Bonneville Dam on the Columbia River.
United States. Bonneville Power Administration.
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Medium-term strategic plan

open access: yes, 2006
"Programme, Budget and Administration Committee of the Executive Board, third meeting, provisional agenda item 3.2""9 January 2006"EBPBAC3/58 ...
World Health Organization. Executive Board. Programme, Budget and Administration Committee. Meeting (3rd : 2006 : Geneva, Switzerland)
core  

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