Results 41 to 50 of about 730,203 (311)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Green shipping networks as drivers of decarbonization in offshore shipping companies

open access: yesMaritime Transport Research, 2022
Within the next 30 years, shipping companies must find their zero-emissions route. However, there is no consensus on which technologies and fuels are the most appropriate to decarbonize shipping.
Agnete Hessevik
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Psychological empowerment as a facilitator for enhancing organizational citizenship behavior: A case study in the healthcare and treatment sector [PDF]

open access: yesفصلنامه ابن سینا
Background and aims: Psychological empowerment is a crucial factor in driving performance improvement within the healthcare and treatment system. As an organizational strategy, it plays a vital role in enabling employees to take on more responsibilities ...
Hossein Samadi Miarkolaei   +1 more
doaj  

Designing a Smart human resources Architecture Model for Medical Sciences Universities

open access: yesSocial Determinants of Health
Background: This study was conducted with the aim of designing the architectural model of human resources of universities of medical sciences in southeastern provinces of Iran with the intelligent approach.
Mohammad Reza Gholami   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Administration development for expressway authority of Thailand

open access: yes, 2013
Dissertation (D.P.A.)--National Institute of Development Administration, 2013.This study is quantitative and qualitative research which mainly aims at studying the development of present Expressway Authority of Thailand (EXAT) administration.
Suchart Chonsakpipat
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Analysing public sector institutional capacity for health workforce governance in the South-East Asia region of WHO

open access: yesHuman Resources for Health, 2019
Background In order to analyse the institutional capacity for health workforce policy development and implementation in countries in the South-East Asia region, the WHO facilitated a cross-sectional analysis of functions performed, structure, personnel ...
Giorgio Cometto   +10 more
doaj   +1 more source

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