Results 91 to 100 of about 1,023,510 (318)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Perceived organizational support, organizational cynicism and employee well-being

open access: yes, 2014
The present study examined how an employee’s perception of their employing organization can impact his or her thoughts, feelings and behaviors. This study examined cognitive, affective and behavioral organizational cynicism in relation to perceived ...
Peplinski, Marin Sara
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Organizational Learning Oriented Model of Organizational Adaptation [PDF]

open access: yes, 2005
This paper proposes an agent-based simulation model for analyzing adaptive processes of organizations with organizational learning. The model is based on a framework of organizational cybernetics and represents organizational activities both decision ...
Takahashi, Shingo, Goto, Yusuke
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The mediator role of organizational innovativeness between organizational culture and organizational effectiveness

open access: yes, 2014
Organizational culture and organizational innovativeness are viewed as important factors for improving the organizational effectiveness in institutions of higher education.
Lope Pihie, Zaidatol Akmaliah   +3 more
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Department of Organizational Leadership, Policy, and Development (OLPD) History Diagram

open access: yes, 2011
Hendel, Darwin; University of Minnesota. Department of Organizational Leadership, Policy, and Development. (2011). Department of Organizational Leadership, Policy, and Development (OLPD) History Diagram. Retrieved from the University Digital Conservancy,
Hendel, Darwin   +1 more
core  

Internationalization process of colombian SMEs

open access: yesManagement Letters/Cuadernos de Gestión, 2009
The Colombian SMEs, like those of Latin America, confront a series of barriers for the export associated to the deficiency of resources and organizational and directive capacities, which cause that their permanence in the international markets is ...
PIEDAD CRISTINA MARTÍNEZ CARAZO
doaj  

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