Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Effect of organizational change on employee innovation performance: A dual mediation model. [PDF]
Liu T +7 more
europepmc +1 more source
How Blockchain Will Change Leadership Strategies for Effectively Managing Organizational Change. [PDF]
Richard R +3 more
europepmc +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Culturally Attuned Leadership and Employee Behavior During Organizational Change Initiatives in a Developing Economy. [PDF]
Kebe IA, Liu Y, Kahl C.
europepmc +1 more source
Midwives' experiences of an organizational change in early postpartum care services in Norway: A qualitative study. [PDF]
Levorstad T +3 more
europepmc +1 more source
Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein +13 more
wiley +1 more source
Readiness to the privatization of the health system in Saudi Arabia: Translation and factor analysis of Readiness to Organizational change (ROC) scale. [PDF]
Alasiri AA, Zhang Q.
europepmc +1 more source
Lean Perspectives in an Organizational Change in a Scientific Direction of an Italian Research Institute: Experience of the Cancer Institute of Bari. [PDF]
La Forgia D +14 more
europepmc +1 more source
Pilihan perubahanWhat are the change options?• Culture• Structure• Technologi• Physical setting ...
openaire +1 more source

