Results 41 to 50 of about 559,162 (302)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Drivers of organizational creativity [PDF]

, 2005
A path model of organizational creativity was presented; it conceptualized the influences of information sharing, learning culture, motivation, and networking on creative climate.
Dimenäs, Elof, Gustafsson, Jan-Eric, Selart, Marcus, Sundgren, Mats   +3 more
core  

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

The Toxic Climate of Organization: Conceptualization and Measurement [PDF]

مطالعات مدیریت بهبود و تحول, 2017
Sometimes the climate of organization, as an organism, is impregnated to toxicity. Since this kind of climate conveys dysfunctional consequences to organization members, it is requisite to explore the dimensions and components of such a climate and also ...
مصطفی هادوی نژاد, سعیده روستایی   +1 more
doaj   +1 more source

Influence of Test Temperature and Test Frequency on Fatigue Life of Aluminum Alloy EN AW‐2618A

Advanced Engineering Materials, EarlyView.
The influence of test temperature and test frequency on the fatigue life of EN AW‐2618A is investigated. High‐cycle fatigue tests are performed at different test temperatures and frequencies on the 1000 h/230°C overaged state. Both test parameters reduce fatigue life due to time‐dependent damage mechanisms.
Ying Han, Julian M. Rosalie, Jan Radners, Mauro Madia, Philipp von Hartrott, Birgit Skrotzki   +5 more
wiley   +1 more source

The Impact of Organizational Climate and Perceived Organizational Support on Organizational Commitment: The Mediating Role of Job Satisfaction

Indonesian Interdisciplinary Journal of Sharia Economics
This research aims to analyze the influence of organizational climate, perceived organizational support, and job satisfaction on Organizational Commitment. The analysis uses Structural Equation Modeling with the Partial Least Square (PLS) approach.
Minti Hari, Herni Justiana Astuti, Naelati Tubastuvi, Iwan Fakhruddin   +3 more
doaj   +1 more source

The Role of Grit in Organizational Performance During a Pandemic

Frontiers in Psychology, 2022
In the context of the organizational crisis caused by COVID-19, scholars and professionals have focused on factors that help employees stay at their jobs and perform well.
Joonghak Lee
doaj   +1 more source

Auto‐Generated Valence States in Electrocatalysts for Boosting Oxygen and Hydrogen Evolution Kinetics in Alkaline Water/Alkaline Seawater/Simulated Seawater/Natural Seawater

Advanced Functional Materials, EarlyView.
This review systematically highlights the latest achievements in mixed‐valence states relevant to hydrogen and oxygen evolution reactions, providing essential insights into future directions and methods for large‐scale practical implementation. This critical review is expected to provide an overview of recent advancements in diverse valence‐state metal
Jitendra N. Tiwari, Gokul Bhaskaran, Krishan Kumar, Yun Suk Huh, Young‐Kyu Han   +4 more
wiley   +1 more source

Organizational factors associated with readiness for change in residential aged care settings

BMC Health Services Research, 2018
Background Organizational change is inevitable in any workplace. Previous research has shown that leadership and a number of organizational climate and contextual variables can affect the adoption of change initiatives.
Kathryn von Treuer, Gery Karantzas, Marita McCabe, David Mellor, Anastasia Konis, Tanya E. Davison, Daniel O’Connor   +6 more
doaj   +1 more source

The Italian Validation of OSCI: The Organizational and Safety Climate Inventory

Safety, 2021
Although safety climate has been the object of multiple studies in the last thirty years, the relationship between safety climate and organizational climate has been scarcely investigated.
Silvia Platania, Anna Paolillo, Silvia A. Silva   +2 more
doaj   +1 more source