Results 71 to 80 of about 1,224,570 (272)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Organizational communication process

open access: yesEkonomski Vjesnik, 2012
Managers spend majority of their time communicating in several forms: meeting, face-to –face dis- cussion, letters, emails etc. Also more and more employees realize that communication is a very im- portant part of their work because a lot of their work
Kenan Spaho
doaj  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Replicating and Extending Soroka, Fournier, and Nir: Negative News Increases Arousal and Negative Affect

open access: yesMedia and Communication
The negativity bias hypothesis in political communication contends that people are more aroused by negative vs. positive news. Soroka et al. (2019) provide evidence for this negativity bias in a study in 17 countries across six continents.
Roeland Dubèl   +4 more
doaj   +1 more source

Website Analysis of Šiauliai Rėkyva Progymnasium in Content and Structural Aspects

open access: yesTaikomieji Moksliniai Tyrimai, 2022
The article analyzes the concept of communication, communication types, channels and tools. It also discusses a certain communication tool–the website. A practical quantitative analysis of Šiauliai Rėkyvos progymnasium's communication website's content ...
Giedrima Načienė, Jurgita Macienė
doaj  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Security dialogues: building better relationships between security and business [PDF]

open access: yes, 2016
In the real world, there's often a discrepancy between an organization's mandated security processes and what actually happens. The social practice of security flourishes in the space between and around formal organizational security processes.
Ashenden, Debi, Lawrence, Darren
core   +1 more source

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel   +5 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy