Results 31 to 40 of about 71,692 (263)

Fictitious Efficiency: What the Russian Survey of Performance of Higher Education Institutions Actually Assessed

Вопросы образования, 2020
Annual Survey of Performance of Higher Education Institutions, conducted in Russia since 2012, was used to identify “inefficient” universities, subject to measures including closure or merging with other schools. As a result of these policies, the number
Katerina Guba, Mikhail Sokolov, Angelika Tsivinskaya   +2 more
doaj   +1 more source

Palliative Care in Portugal—From Intention to Reality, What Is Yet to Be Accomplished

Nursing Reports, 2023
Objectives: This article focuses on exploring the evolution of palliative care in Portugal. Ten years after the approval of its Basic Law, the aim was to investigate the quality of the path followed and the guidelines that could promote its development ...
Paulo Marques, Francisca Rêgo, Rui Nunes   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Couching as Technology and Effective Way of Personnel Development in Commercial Organization

Вестник Российского экономического университета имени Г. В. Плеханова
According to executives and business proprietors, current methods of company management are losing efficiency, which is especially evident in conditions of quickly changing world and growing information flows.
A. L. Barannikov, L. E. Zhuravleva, T. A. Levochkina   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The impact of intellectual capital on ROA as a significant indicator of financial performance

BizInfo
In the modern business, organizations that recognize the value of intellectual resources and incorporate them into their business strategy have a greater chance of long-term success.
Ana Urosević, Ana Dukić, Zlatomir Markovic   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Kaizen as a system for strategic cost management in the realization of competitive advantages [PDF]

Ekonomija: teorija i praksa, 2020
Managing a company in contemporary, dynamic business conditions must be strategically oriented. The competition forces companies to constantly reduce all types of costs incurred in preproduction and production processes, with the obligation to maintain ...
Jolović Ivana, Petkovič Đerđi
doaj