Results 51 to 60 of about 4,487,035 (306)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Presenting the Interpretive Structural Model of Fearless Organization Drivers in Social Security Hospitals [PDF]

Taṣvīr-i salāmat
Background. Today, psychological security, the prevalence of a supportive organizational climate, and the transformation of organizations into secure environments are of paramount importance.
Fatemeh Sadat Vahabzadeh Moghadam, Ahmad Vedadi, Karam Allah Daneshfard   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The Impact of Digital Transformation on the Performance of SMEs in Romania: Empirical Evidence on Competitiveness and Organizational Efficiency [PDF]

Annals of the University of Oradea: Economic Science
Digital transformation has become a strategic determinant of firm performance in competitive and technology-driven business environments. For small and medium-sized enterprises, the adoption of digital tools and digitally enabled processes is essential ...
Ci rian-Constantin PĂTRĂUCEANU, Oleg PETELCA, Iurie BEȘLIU, Veronica GARBUZ   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The Effect of Implementing AI on Job Burnout Through the Mediating Role of Work-Life Balance in the Context of HRM

ECONOMICS
The rapid integration of Artificial Intelligence (AI) into Human Resource Management (HRM) practices has significantly transformed organizational operations.
AlOqaily Ahmad Nader, Qawasmeh Esraa Farid, Tawalbeh Jawad   +2 more
doaj   +1 more source

Theoretical and methodological matters of organizational culture [PDF]

Civilizar, 2010
This paper is concerned with Organizational Culture (OC), its components and the main techniques to study it. It states that measuring and establishing its impacts related with results, efficiency, healthy and welfare of employees are important issues ...
Claudia Eugenia Toca Torres, Jesús Carrillo Rodríguez   +1 more
doaj  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source