Results 61 to 70 of about 4,487,035 (306)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
European PsychiatryBackground The use of coercive measures is an increasingly debated aspect of psychiatric treatment. Considering the multitude of negative effects, patients, clinicians, and ethicists alike have called for a more cautious application of coercion.
Cornelius Müller +5 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
THE OUTSOURCING STRATEGIES FOR ORGANIZATIONAL EFFECTIVENESS AND EFFICIENCY
Jurnal Aplikasi Bisnis, 2006 Outsourcing is a management strategy by which an organization delegate major, non-core functions to specialized and efficient service providers. Outsourcing represents a significant shift in the way organizations manage and staff business support activities.
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Couching as Technology and Effective Way of Personnel Development in Commercial Organization
Вестник Российского экономического университета имени Г. В. ПлехановаAccording to executives and business proprietors, current methods of company management are losing efficiency, which is especially evident in conditions of quickly changing world and growing information flows.
A. L. Barannikov +2 more
doaj +1 more source
Organizacija, 2015 Background: Literature defines different types of flexibility and security with regard to work. Regardless of which type of flexibility or security is discussed, the consequences for individuals, organizations or employers and society are significant.
Kozjek Tatjana, Ferjan Marko
doaj +1 more source
The Combined Use of Balanced Scorecard and Data Envelopment Analysis in the Banking Industry
Business Systems Research, 2020 Background: Starting from the limitations of different single-method approaches to measuring the organizational efficiency, the paper is focused on covering both the financial and non-financial factors of this concept by combining two methods, namely the
Bošković Aleksandra, Krstić Ana
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
National Action Plan for Energy Efficiency, Chapter 6: Energy Efficiency Program Best Practices
, 2006 Chapter from the National Action Plan for Energy Efficiency documenting key findings from energy efficiency programs that have been successfully operating for many ...
National Action Plan for Energy Efficiency (U.S.)
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