Results 121 to 130 of about 193,824 (315)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Motivating Organizational Search [PDF]
This paper investigates the value of high-powered incentives for motivating search for novelty in business organizations. While organizational search critically depends on the individual efforts of employees, motivating search effort is challenged by ...
Nils Stieglitz, Oliver Baumann
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Sleep Breathing Disorders in the COVID-19 Era: Italian Thoracic Society Organizational Models for a Correct Approach to Diagnosis and Treatment. [PDF]
Respiration, 2020 Insalaco G +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Modelling relationship quality across organizational cultures : an empirical investigation within the logistics outsourcing industry [PDF]
Relationship quality is the cornerstone of relationship marketing. However, conceptualizations of relationship quality vary across studies indicating the absence of a general consensus. Consistent with the definition of Hennig-Thurau et al.
Palaima, Tomas
core
, 2014 Purpose: Taking into account the need to make a clearer distinction between traditional and new organizational controls, this paper aims to investigate similarities and differences between those two forms and explore the extent to which new forms of ...
Ofelia A. Palermo +8 more
core +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Leadership, Organizational Learning and Performance in Small and Medium Firms [PDF]
CEO's leadership is an organizational dimension that has not been carefully studied in the literature on small firms. Particularly, as organizational learning is now anchored as an important part of the building and sustaining of the small and medium ...
François Therin
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How could knowledge of sensemaking during organizational change contribute to the investigation of how sense is made of organizational perfomance [PDF]
, 2011 Managers and organizational stakeholders are confronted by a range of stimuli, emotions, events, data, paradoxes and ambiguities in endeavouring to understand and make sense of change and the performance of their organizations.
Allen, Richard
core
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source