Results 151 to 160 of about 193,824 (315)

Organizational learning: Where do we stand? Where do we want to go? [PDF]

The field of organizational learning has developed dynamically but is not ready for closure. This article reviews the cultural contexts in which research on organizational learning has been conducted since the 1960s, and the intellectual traditions that ...
Antal, Ariane Berthoin, Dierkes, Meinolf
core  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Theorizing and strategizing with models: Generative models of business models [PDF]

The ambiguity surrounding model-based science is exemplified by the proliferation of meanings of the term "business model". We argue that a clearer specification of the analytical, theoretical and ontological validity of models is an opportunity to learn
Seelos, Christian
core  

Health economic analysis of organizational models for breast cancer surgery: a bottom-up micro-costing and cost-minimization approach. [PDF]

Health Econ Rev
Eriksson J, Meili KW, Lindholm L, Appelblad M, Sund M.   +4 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

KNOWEDGE DEVELOPMENT WITHIN COMMUNITIES OF PRACTICE USING ORGANIZATIONAL LEARNING [PDF]

Knowledge assets are a critical resource that can generate a competitive advantage for organizations. Generally, knowledge can be divided in explicit knowledge and tacit knowledge.
Iulia Mărieș, Emil Scarlat
core  

Integrated Hospital-Territory Organizational Models and the Role of Family and Community Nurses in the Management of Chronic Conditions: A Scoping Review. [PDF]

Medicina (Kaunas)
Azzellino G, Vagnarelli P, Passamonti M, Mengoli L, Ginaldi L, De Martinis M.   +5 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

The Ligurian Experience in the Management of Lung Cancer: Organizational Models and New Perspectives. [PDF]

Healthcare (Basel)
Amicizia D, Marchini F, Pronzato P, Paoli G, Genova C, Allegretti S, Ansaldi F.   +6 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source