Results 171 to 180 of about 193,824 (315)
Managing the tensions of innovation and efficiency in the pursuit of organizational ambidexterity [PDF]
Whereas organizational ambidexterity is increasingly gaining ground in organizational theory, key issues regarding how ambidexterity is conceptualized, achieved and sustained offer partial insights or remain unexplored.
Papachroni, Angeliki
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Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Informants in Organizational Marketing Research
Organizational research frequently involves seeking judgmental data from multiple informants within organizations. Researchers are often faced with determining how many informants to survey, who those informants should be and (if more than one) how best ...
Lilien, G.L. +2 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Synergistic effects of organizational innovation practices and firm performance
Organizational innovation has been shown to be favourable for technological innovation. However, the question of which organizational practices should be combined ? and thus of their compatibility ? remains unanswered. We here empirically investigate the
NGUYEN-VAN Phu +2 more
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Knowledge Management What Can Organizational Economics Contribute? [PDF]
Knowledge management has emerged as a very successful organization practice and has been extensively treated in a large body of academic work. Surprisingly, however, organizational economics (i.e., transaction cost economics, agency theory, team theory ...
Nicolaj J. Foss, Volker Mahnke
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Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Do firms rely on sources of information for organizational innovation?
The growing literature on knowledge and information has focused on the impact of information sources on technological innovation. Our objective was to explore the use made by firms of internal and external (market, research and generally available ...
NGUYEN Thi Thuc Uyen, MOTHE Caroline
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Organizational Climate and Company Productivity: the Role of Employee Affect and Employee Level [PDF]
Consistent with a growing number of models about affect and behaviour and with arecognition that perception alone provides no impetus for action, it was predicted thatassociations between company climate and productivity would be mediated by average ...
M West, P Warr, M Patterson
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source