Results 141 to 150 of about 3,294,732 (304)

HUMAN RESOURCES PERFORMANCE EVALUATION METHODS [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
The evaluation of human resource (HR) performance is a critical component in enhancing organizational effectiveness and achieving strategic objectives. As organizations, both public and private, face increasing demands for efficiency, innovation, and
TOMESCU-DUMITRESCU CORNELIA
doaj  

Kurt Lewin: Organizational Change

open access: yes, 2019
I cover the life, career, and contributions of the German-born and trained psychologistKurt Lewin, whose primary contribution to management thought wasdescribing the process of organizational change. I argue that Lewin, despite thetime in which he lived,
Muldoon, Jeffrey
core  

Organizational downsizing [PDF]

open access: yes, 1999
Plan BAlthough reports of job losses due to corporate restructuring are commonplace, close examination reveals that downsizing may not be the solution.
Kang, Hyun-gu
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Organizational scenarios for the use of learning objects

open access: yes, 2006
Organizational scenarios presents the following three scenarios for working with learning objects in Dutch higher education and institutions: Scenario 1: Self-regulation (community scenario) Scenario 2: Institutional regulation Scenario 3: Network organization This document is aimed at policy makers and educational technology consultants.
Hermans, Henry, De Vries, Fred
openaire   +2 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Organizational knowledge dynamics [PDF]

open access: yes
The paper addresses the main issues concerning knowledge conceptualization and knowledge dynamics, in the context of Romanian organizations. The links between organizational knowledge, organizational learning and organizational culture are being ...
Simona VASILACHE
core  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

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