Results 71 to 80 of about 34,600 (265)

Product, Organizational and Performance Effects of Product Modularity [PDF]

open access: yes, 2014
A lot has been written about the performance effects associated withimplementing a higher degree of product modularity in a firm’s productportfolio. However, these findings are mostly based on case research in theelectronics and automotive industries and have hardly been tested andgeneralized beyond these industries.
openaire   +3 more sources

Building Evidence for Active Work Through a Bibliometric Review of Employee Physical Activity and Job Performance

open access: yesEconomic and Business Review
Physical activity (PA) is widely recognized as beneficial for employee health and well-being, yet research linking employee PA to job performance remains fragmented across disciplines, outcome conceptualizations, and theoretical perspectives.
Tamara Stanković, Alenka Slavec Gomezel
doaj   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min   +6 more
wiley   +1 more source

A Rare Allele of ST5 From Wild Rice Enhances Salt Tolerance in Rice

open access: yesAdvanced Science, EarlyView.
A novel salt‐tolerance gene ST5W, characterized by a unique 36‐bp promoter insertion, is found exclusively in a small subset of Oryza rufipogon and is absent in cultivated rice. Field trials confirm ST5W significantly enhances rice yield across diverse genetic backgrounds under saline conditions.
Meng Xing   +26 more
wiley   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

open access: yesAdvanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang   +11 more
wiley   +1 more source

The Influence of Organizational Culture and Organizational Climate on Employee Productivity at PT. Rajawali Nusindo Medan Branch

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
This research was conducted to determine Organizational Culture and Organizational Climate on Work Productivity, this research uses quantitative methods with an associative approach. In this study the population of employees working at PT.
Juita Manalu   +2 more
doaj   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou   +12 more
wiley   +1 more source

An Approach to the Selection of Optimal Transformation Strategy in Seaports

open access: yesPromet (Zagreb), 2010
After theoretical considerations of organizational changes, the research findings were presented in relation to the following: the selection of the optimal model for implementation of organizational changes in the port that is subject of analysis and ...
Deda Đelović   +1 more
doaj   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

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